Myofibroblasts

B Hinz - Experimental eye research, 2016 - Elsevier
Myofibroblasts are activated in response to tissue injury with the primary task to repair lost or
damaged extracellular matrix. Enhanced collagen secretion and subsequent contraction …

[HTML][HTML] A review of structural and biomechanical changes in the cornea in aging, disease, and photochemical crosslinking

BJ Blackburn, MW Jenkins, AM Rollins… - … in bioengineering and …, 2019 - frontiersin.org
The study of corneal biomechanics is motivated by the tight relationship between
biomechanical properties and visual function within the ocular system. For instance …

Biomechanics and structure of the cornea: implications and association with corneal disorders

J Ma, Y Wang, P Wei, V Jhanji - Survey of ophthalmology, 2018 - Elsevier
Recent studies have shown that alterations in corneal biomechanical properties are
associated with corneal pathologies, particularly corneal ectasia. Moreover, these …

Mimicking the natural basement membrane for advanced tissue engineering

P Jain, SB Rauer, M Möller, S Singh - Biomacromolecules, 2022 - ACS Publications
Advancements in the field of tissue engineering have led to the elucidation of physical and
chemical characteristics of physiological basement membranes (BM) as specialized forms of …

Regulation of corneal stroma extracellular matrix assembly

S Chen, MJ Mienaltowski, DE Birk - Experimental eye research, 2015 - Elsevier
The transparent cornea is the major refractive element of the eye. A finely controlled
assembly of the stromal extracellular matrix is critical to corneal function, as well as in …

[HTML][HTML] A chemomechanical model for nuclear morphology and stresses during cell transendothelial migration

X Cao, E Moeendarbary, P Isermann, PM Davidson… - Biophysical journal, 2016 - cell.com
It is now evident that the cell nucleus undergoes dramatic shape changes during important
cellular processes such as cell transmigration through extracellular matrix and endothelium …

Squishy matters–Corneal mechanobiology in health and disease

SM Thomasy, BC Leonard, MA Greiner… - Progress in retinal and …, 2024 - Elsevier
The cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces
in order to maintain its structural integrity, barrier function, transparency and refractive …

[HTML][HTML] Biomaterials-enabled cornea regeneration in patients at high risk for rejection of donor tissue transplantation

MM Islam, O Buznyk, JC Reddy… - NPJ Regenerative …, 2018 - nature.com
The severe worldwide shortage of donor organs, and severe pathologies placing patients at
high risk for rejecting conventional cornea transplantation, have left many corneal blind …

Structuring of hydrogels across multiple length scales for biomedical applications

ME Cooke, SW Jones, B Ter Horst… - Advanced …, 2018 - Wiley Online Library
The development of new materials for clinical use is limited by an onerous regulatory
framework, which means that taking a completely new material into the clinic can make …

A rethinking of collagen as tough biomaterials in meat packaging: assembly from native to synthetic

X Tian, KX Zhao, A Teng, Y Li… - Critical Reviews in Food …, 2024 - Taylor & Francis
Due to the high moisture-associated typical rheology and the changeable and harsh
processing conditions in the production process, packaging materials for meat products …