Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Poloxamers, also known as Pluronics®, are block copolymers of poly (ethylene oxide)(PEO)
and poly (propylene oxide)(PPO), which have an amphiphilic character and useful …

During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …

Most of the administered anti-cancer drugs are hydrophobic in nature and are known to
have poor water solubility, short residence time, rapid clearance from the body and systemic …

Cabazitaxel, a novel tubulin inhibitor with poor affinity for P-glycoprotein, is a second-
generation taxane holding great promise for the treatment of metastatic castration-resistant …

Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …

Dual-targeting nanoparticle drug delivery system was developed by conjugating Angiopep
with PEG–PCL nanoparticles (ANG-NP) through bifunctional PEG to overcome the …

Nanotechnology, in health and medicine, extensively improves the safety and efficacy of
different therapeutic agents, particularly the aspects related to drug delivery and targeting …