Dynamics and functions of lipid droplets
JA Olzmann, P Carvalho - Nature reviews Molecular cell biology, 2019 - nature.com
Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …
The ménage à trois of autophagy, lipid droplets and liver disease
Y Filali-Mouncef, C Hunter, F Roccio, S Zagkou… - Autophagy, 2022 - Taylor & Francis
Autophagic pathways cross with lipid homeostasis and thus provide energy and essential
building blocks that are indispensable for liver functions. Energy deficiencies are …
building blocks that are indispensable for liver functions. Energy deficiencies are …
Lipid droplets in the nervous system
Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …
physiological state of cells. In addition to controlling cell metabolism, they play a protective …
Lipid droplet biogenesis
TC Walther, J Chung… - Annual review of cell and …, 2017 - annualreviews.org
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
Expanding roles for lipid droplets
MA Welte - Current biology, 2015 - cell.com
Lipid droplets are the intracellular sites for neutral lipid storage. They are critical for lipid
metabolism and energy homeostasis, and their dysfunction has been linked to many …
metabolism and energy homeostasis, and their dysfunction has been linked to many …
A proximity labeling strategy provides insights into the composition and dynamics of lipid droplet proteomes
Lipid droplet (LD) functions are regulated by a complement of integral and peripheral
proteins that associate with the bounding LD phospholipid monolayer. Defining the …
proteins that associate with the bounding LD phospholipid monolayer. Defining the …
Lipid droplets and cellular lipid metabolism
TC Walther, RV Farese Jr - Annual review of biochemistry, 2012 - annualreviews.org
Among organelles, lipid droplets (LDs) uniquely constitute a hydrophobic phase in the
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
Biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites
Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all
eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and …
eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and …
Not just fat: the structure and function of the lipid droplet
T Fujimoto, RG Parton - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
Cellular pathways of hereditary spastic paraplegia
C Blackstone - Annual review of neuroscience, 2012 - annualreviews.org
Human voluntary movement is controlled by the pyramidal motor system, a long CNS
pathway comprising corticospinal and lower motor neurons. Hereditary spastic paraplegias …
pathway comprising corticospinal and lower motor neurons. Hereditary spastic paraplegias …