Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes the corona virus
disease-19 which is accompanied by severe pneumonia, pulmonary alveolar collapses and …

Background Mortality and morbidity due to neonatal sepsis and necrotising enterocolitis
(NEC) remain high despite the use of potent antimicrobial agents. Agents that modulate …

The type 2 coronavirus causes severe acute respiratory syndrome (SARS-CoV-2) and
produces pneumonia with pulmonary alveolar collapse. In some cases it also causes sepsis …

Sepsis is at present one of the leading causes of morbidity and mortality in the neonatal
population. Together with inflammation, oxidative stress is involved in detrimental pathways …

Despite continued advances in neonatal medicine, sepsis remains a leading cause of death
worldwide in neonatal intensive care units. The clinical presentation of sepsis in neonates …

Despite progress in understanding the pathophysiology of acute lung damage, currently
approved treatment possibilities are limited to lung-protective ventilation, prone positioning …

Objective Current knowledge on the global burden of infant sepsis is limited to population-
level data. We aimed to summarize global case fatality rates (CFRs) of young infants with …

Background The lack of a consensus definition of neonatal sepsis and a core outcome set
(COS) proves a substantial impediment to research that influences policy and practice …

The first days of postnatal life are energetically demanding as metabolic functions change
dramatically to accommodate drastic environmental and physiologic transitions after birth. It …

Background: Toll-like receptor (TLR)-mediated inflammation may contribute to neonatal
sepsis, for which pentoxifylline (PTX), a phosphodiesterase inhibitor that raises intracellular …