[HTML][HTML] Is antioxidant therapy a useful complementary measure for Covid-19 treatment? An algorithm for its application
ME Soto, V Guarner-Lans, E Soria-Castro… - Medicina, 2020 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes the corona virus
disease-19 which is accompanied by severe pneumonia, pulmonary alveolar collapses and …
disease-19 which is accompanied by severe pneumonia, pulmonary alveolar collapses and …
Pentoxifylline for treatment of sepsis and necrotising enterocolitis in neonates
M Pammi, KN Haque - Cochrane Database of Systematic …, 2023 - cochranelibrary.com
Background Mortality and morbidity due to neonatal sepsis and necrotising enterocolitis
(NEC) remain high despite the use of potent antimicrobial agents. Agents that modulate …
(NEC) remain high despite the use of potent antimicrobial agents. Agents that modulate …
[HTML][HTML] Antioxidants and pentoxifylline as coadjuvant measures to standard therapy to improve prognosis of patients with pneumonia by COVID-19
AP Chavarría, RRV Vázquez, JGD Cherit… - Computational and …, 2021 - Elsevier
The type 2 coronavirus causes severe acute respiratory syndrome (SARS-CoV-2) and
produces pneumonia with pulmonary alveolar collapse. In some cases it also causes sepsis …
produces pneumonia with pulmonary alveolar collapse. In some cases it also causes sepsis …
Sepsis and oxidative stress in the newborn: from pathogenesis to novel therapeutic targets
C Poggi, C Dani - Oxidative medicine and cellular longevity, 2018 - Wiley Online Library
Sepsis is at present one of the leading causes of morbidity and mortality in the neonatal
population. Together with inflammation, oxidative stress is involved in detrimental pathways …
population. Together with inflammation, oxidative stress is involved in detrimental pathways …
[HTML][HTML] Immunomodulation to prevent or treat neonatal sepsis: past, present, and future
Despite continued advances in neonatal medicine, sepsis remains a leading cause of death
worldwide in neonatal intensive care units. The clinical presentation of sepsis in neonates …
worldwide in neonatal intensive care units. The clinical presentation of sepsis in neonates …
[HTML][HTML] Phosphodiesterase inhibitors in acute lung injury: what are the perspectives?
D Mokra, J Mokry - International Journal of Molecular Sciences, 2021 - mdpi.com
Despite progress in understanding the pathophysiology of acute lung damage, currently
approved treatment possibilities are limited to lung-protective ventilation, prone positioning …
approved treatment possibilities are limited to lung-protective ventilation, prone positioning …
[HTML][HTML] Contemporary trends in global mortality of sepsis among young infants less than 90 days: a systematic review and meta-analysis
MY Gan, WL Lee, BJ Yap, STT Seethor… - Frontiers in …, 2022 - frontiersin.org
Objective Current knowledge on the global burden of infant sepsis is limited to population-
level data. We aimed to summarize global case fatality rates (CFRs) of young infants with …
level data. We aimed to summarize global case fatality rates (CFRs) of young infants with …
[HTML][HTML] Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials
CJ Henry, G Semova, E Barnes, I Cotter, T Devers… - Pediatric …, 2022 - nature.com
Background The lack of a consensus definition of neonatal sepsis and a core outcome set
(COS) proves a substantial impediment to research that influences policy and practice …
(COS) proves a substantial impediment to research that influences policy and practice …
Immunometabolic approaches to prevent, detect, and treat neonatal sepsis
The first days of postnatal life are energetically demanding as metabolic functions change
dramatically to accommodate drastic environmental and physiologic transitions after birth. It …
dramatically to accommodate drastic environmental and physiologic transitions after birth. It …
[HTML][HTML] Pentoxifylline inhibits TLR-and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in …
EM Speer, DJ Dowling, LS Ozog, J Xu, J Yang… - Pediatric …, 2017 - nature.com
Background: Toll-like receptor (TLR)-mediated inflammation may contribute to neonatal
sepsis, for which pentoxifylline (PTX), a phosphodiesterase inhibitor that raises intracellular …
sepsis, for which pentoxifylline (PTX), a phosphodiesterase inhibitor that raises intracellular …