Tooth slice/scaffold model of dental pulp tissue engineering

VT Sakai, MM Cordeiro, Z Dong… - Advances in dental …, 2011 - journals.sagepub.com
Multipotency is a defining characteristic of post-natal stem cells. The human dental pulp
contains a small subpopulation of stem cells that exhibit multipotency, as demonstrated by …

Promotion of natural tooth repair by small molecule GSK3 antagonists

VCM Neves, R Babb, D Chandrasekaran, PT Sharpe - Scientific reports, 2017 - nature.com
The restoration of dentine lost in deep caries lesions in teeth is a routine and common
treatment that involves the use of inorganic cements based on calcium or silicon-based …

The impact of bioactive molecules to stimulate tooth repair and regeneration as part of restorative dentistry

M Goldberg, S Lacerda-Pinheiro, N Jegat, N Six… - Dental …, 2006 - dental.theclinics.com
For years, dental surgeons have used a limited number of capping agents to keep teeth
alive. The most efficient was calcium hydroxide. Lessons from developmental biology have …

In vitro characterization of human dental pulp cells: various isolation methods and culturing environments

GTJ Huang, W Sonoyama, J Chen, SH Park - Cell and tissue research, 2006 - Springer
Our purpose was to characterize human dental pulp cells isolated by various methods and
to examine the behavior of cells grown under various conditions for the purpose of …

In vitro bioactivity of Bioroot™ RCS, via A4 mouse pulpal stem cells

S Dimitrova-Nakov, E Uzunoglu, H Ardila-Osorio… - Dental Materials, 2015 - Elsevier
Objective To evaluate the biocompatibility and osteoinductive properties of Bioroot™ RCS
(BR, Septodont, France) compared to Kerr's Pulp Canal Sealer™(PCS, Kerr, Italy) using the …

KDM6B epigenetically regulates odontogenic differentiation of dental mesenchymal stem cells

J Xu, B Yu, C Hong, CY Wang - International Journal of Oral Science, 2013 - nature.com
Mesenchymal stem cells (MSCs) have been identified and isolated from dental tissues,
including stem cells from apical papilla, which demonstrated the ability to differentiate into …

Phosphate induces formation of matrix vesicles during odontoblast-initiated mineralization in vitro

SC Chaudhary, M Kuzynski, M Bottini, E Beniash… - Matrix Biology, 2016 - Elsevier
Mineralization is a process of deposition of calcium phosphate crystals within a fibrous
extracellular matrix (ECM). In mineralizing tissues, such as dentin, bone and hypertrophic …

Essential role of osterix for tooth root but not crown dentin formation

H Zhang, Y Jiang, C Qin, Y Liu, SP Ho, JQ Feng - 2015 - academic.oup.com
Tooth is made of crown and root. It is widely believed that dentin formation in crown and root
uses the same regulatory mechanism. However, identification of nuclear factor 1 C (NFIC)'s …

[HTML][HTML] Reactive oxygen species (ROS) generation as an underlying mechanism of inorganic phosphate (Pi)-induced mineralization of osteogenic cells

S Khalid, H Yamazaki, M Socorro, D Monier… - Free Radical Biology …, 2020 - Elsevier
Abstract Reactive Oxygen Species (ROS) are a natural byproduct of oxygen metabolism. At
physiological levels, ROS regulate multiple cellular processes like proliferation, migration …

Pulp stem cells: implication in reparative dentin formation

S Dimitrova-Nakov, A Baudry, Y Harichane… - Journal of …, 2014 - Elsevier
Many dental pulp stem cells are neural crest derivatives essential for lifelong maintenance of
tooth functions and homeostasis as well as tooth repair. These cells may be directly …