Drug insight: selective agonists and antagonists of the glucocorticoid receptor
A McMaster, DW Ray - Nature Clinical Practice Endocrinology & …, 2008 - nature.com
Glucocorticoid hormones exert a wide spectrum of metabolic and immunological effects.
They function through the glucocorticoid receptor, a member of the nuclear receptor …
They function through the glucocorticoid receptor, a member of the nuclear receptor …
How do glucocorticoids cause hypertension: role of nitric oxide deficiency, oxidative stress, and eicosanoids
SLH Ong, JA Whitworth - Endocrinology and Metabolism …, 2011 - endo.theclinics.com
The discovery of the anti-inflammatory effects of corticosteroid hormones by Philip Hench
and colleagues in 1929 revolutionized the treatments of various inflammatory conditions …
and colleagues in 1929 revolutionized the treatments of various inflammatory conditions …
Oleanolic acid prevents glucocorticoid‐induced hypertension in rats
SS Bachhav, SD Patil, MS Bhutada… - Phytotherapy …, 2011 - Wiley Online Library
The present study was designed to evaluate the antihypertensive activity of oleanolic acid
isolated from Viscum articulatum, Burm.(Loranthaceae) in glucocorticoid (dexamethasone) …
isolated from Viscum articulatum, Burm.(Loranthaceae) in glucocorticoid (dexamethasone) …
Folic acid ameliorates celecoxib cardiotoxicity in a doxorubicin heart failure rat model
Context: The cardiotoxic effect of selective cyclo-oxygenase-2 inhibitors is well known. While
rofecoxib and valdecoxib have been withdrawn, celecoxib remains on the market. Folic acid …
rofecoxib and valdecoxib have been withdrawn, celecoxib remains on the market. Folic acid …
Effect of dexmedetomidine and cold stress in a rat model of neuropathic pain: Role of interleukin-6 and tumor necrosis factor-α
HSM Farghaly, AM Mahmoud… - European journal of …, 2016 - Elsevier
Dexmedetomidine (Dex) is a novel Alpha 2-adrenoceptor agonist. It decreases sympathetic
tone and attenuates the stress responses to anesthesia and surgery. People exposed to …
tone and attenuates the stress responses to anesthesia and surgery. People exposed to …
Folic acid attenuates vascular endothelial cell injury caused by hypoxia via the inhibition of ERK1/2/NOX4/ROS pathway
F Cheng, J Lan, W Xia, C Tu, B Chen, S Li… - Cell Biochemistry and …, 2016 - Springer
Coronary artery disease is a disease with high morbidity and mortality, in which vascular
endothelial dysfunction plays an important role. Hypoxia leads to the inflammation and …
endothelial dysfunction plays an important role. Hypoxia leads to the inflammation and …
[HTML][HTML] Oleanolic acid prevents increase in blood pressure and nephrotoxicity in nitric oxide dependent type of hypertension in rats
SS Bachhav, MS Bhutada, SP Patil… - Pharmacognosy …, 2015 - ncbi.nlm.nih.gov
Background: Recently, we have reported antihypertensive activity of oleanolic acid (OA) in
glucocorticoid-induced hypertension with restoration of nitric oxide (NO) level. However, the …
glucocorticoid-induced hypertension with restoration of nitric oxide (NO) level. However, the …
Mechanisms of dexamethasone-induced hypertension
SLH Ong, Y Zhang, JA Whitworth - Current Hypertension …, 2009 - ingentaconnect.com
Hypertension is a well-recognized complication of excess glucocorticoids, both naturally-
occurring and synthetic. Dexamethasone is a potent synthetic glucocorticoid, which has …
occurring and synthetic. Dexamethasone is a potent synthetic glucocorticoid, which has …
Folic acid administration prevents ouabain‐induced hyperlocomotion and alterations in oxidative stress markers in the rat brain
Brocardo PS, Budni J, Pavesi E, Franco JL, Uliano‐Silva M, Trevisan R, Terenzi MG, Dafre
AL, Rodrigues ALS. Folic acid administration prevents ouabain‐induced hyperlocomotion …
AL, Rodrigues ALS. Folic acid administration prevents ouabain‐induced hyperlocomotion …
The effect of folic acid throughout pregnancy among pregnant women at high risk of pre-eclampsia: A randomized clinical trial
L Zheng, J Huang, H Kong, F Wang, Y Su, H Xin - Pregnancy hypertension, 2020 - Elsevier
Background Pre-eclampsia is a serious hypertension disease that occurs during pregnancy.
Folic acid (FA) supplementation has been reported to reduce pre-eclampsia risk in pregnant …
Folic acid (FA) supplementation has been reported to reduce pre-eclampsia risk in pregnant …