[HTML][HTML] Surfactant protein A and surfactant protein D variation in pulmonary disease

GL Sorensen, S Husby, U Holmskov - Immunobiology, 2007 - Elsevier
Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

The role of surfactant in asthma

JM Hohlfeld - Respiratory research, 2001 - Springer
Pulmonary surfactant is a unique mixture of lipids and surfactant-specific proteins that covers
the entire alveolar surface of the lungs. Surfactant is not restricted to the alveolar …

Differential proteomic analysis of bronchoalveolar lavage fluid in asthmatics following segmental antigen challenge* S

J Wu, M Kobayashi, EA Sousa, W Liu, J Cai… - Molecular & Cellular …, 2005 - ASBMB
Allergic asthma is characterized by persistent airway inflammation and remodeling.
Bronchoalveolar lavage conducted with fiberoptic bronchoscopy has been widely used for …

The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease

MP Keane, RM Strieter - Respiratory research, 2001 - Springer
The lung responds to a variety of insults in a remarkably consistent fashion but with
inconsistent outcomes that vary from complete resolution and return to normal to the …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

Bronchoalveolar lavage fluid surfactant protein-A and surfactant protein-D are inversely related to inflammation in early cystic fibrosis

TL Noah, PC Murphy, JJ Alink, MW Leigh… - American journal of …, 2003 - atsjournals.org
The pulmonary collectins surfactant protein (SP)-A and SP-D play important roles in innate
lung defense, enhancing opsonization of microbes and limiting lung inflammatory …

Surfactant protein D: a lung specific biomarker in COPD?

DD Sin, PS Pahlavan, SFP Man - Therapeutic advances in …, 2008 - journals.sagepub.com
A major impediment in the development of novel drugs for chronic obstructive pulmonary
disease (COPD) has been the scarcity of a well-validated, robust, and easily obtainable …

Major house dust mite allergens Dermatophagoides pteronyssinus 1 and Dermatophagoides farinae 1 degrade and inactivate lung surfactant proteins A and D

R Deb, F Shakib, K Reid, H Clark - Journal of Biological Chemistry, 2007 - ASBMB
Lung surfactant proteins (SP) A and D are calcium-dependent carbohydrate-binding
proteins. In addition to playing multiple roles in innate immune defense such as bacterial …

IL-4 and IL-13 form a negative feedback circuit with surfactant protein-D in the allergic airway response

A Haczku, Y Cao, G Vass, S Kierstein… - The Journal of …, 2006 - journals.aai.org
The innate immune molecule surfactant protein-D (SP-D) plays an important regulatory role
in the allergic airway response. In this study, we demonstrate that mice sensitized and …

Hookworm-induced persistent changes to the immunological environment of the lung

JJ Reece, MC Siracusa, TL Southard… - Infection and …, 2008 - Am Soc Microbiol
ABSTRACT A number of important helminth parasites of humans have incorporated short-
term residence in the lungs as an obligate phase of their life cycles. The significance of this …