The advent of new genomic techniques has raised expectations that central questions of
mixture toxicology such as for mechanisms of low dose interactions can now be answered …

Ecotoxicological assessment relies to a large extent on the information gathered with
surrogate species and the extrapolation of test results across species and different levels of …

The purpose of this project was to summarise the state of the science on combined actions
of chemicals in food through dissimilar modes of action and to propose a science …

Abstract Biological Response Indicator Devices Gauging Environmental Stressors
(BRIDGES) is a bioanalytical tool that combines passive sampling with the embryonic …

In the natural environment, toxicant effects can be monitored by the signature mRNA
expression patterns of genes that they generate in test organisms. The specificity and …

Abstract Polycyclic Aromatic Hydrocarbons (PAHs) form a family of compounds that are
generally found in complex mixtures. PAHs can lead to the development of carcinogenesis …

Background: Humans and environmental organisms are constantly exposed to complex
mixtures of chemicals. Extending our knowledge about the combined effects of chemicals is …

Pesticides are nearly ubiquitous in surface waters of the United States, where they often are
found as mixtures. The molecular mechanisms underlying the toxic effects of sub-lethal …

No chemical properties have been found to be a reliable predictor of metal toxicity, attributed
to the influence of various specific processes on metal toxicokinetics and toxicodynamics …

The recognized and unknown risks associated with the ever-increasing number of pollutants
in our environment presents a serious threat to us all. This poses a pressing need for a …