Polyacrylic acid-based drug delivery systems: A comprehensive review on the state-of-art

G Dalei, S Das - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
Polyacrylic acid (PAA)-based drug carrier systems have garnered much significance
towards the delivery of various therapeutic agents via different administration routes for the …

Overview on therapeutic applications of microparticulate drug delivery systems

S Bale, A Khurana, ASS Reddy… - Critical Reviews™ in …, 2016 - dl.begellhouse.com
Research in novel drug delivery systems is being explored competitively in order to attain
maximum therapeutic effect while minimizing the adverse effects. Despite several …

Advanced formulations for intranasal delivery of biologics

J Rohrer, N Lupo, A Bernkop-Schnürch - International Journal of …, 2018 - Elsevier
Introduction The global biologics market has been ever increasing over the last decades
and is predicted to top Euro 350 by 2020. Facing this scenario, the parenteral route of …

Thiolated polymers: An overview of mucoadhesive properties and their potential in drug delivery via mucosal tissues

K Mfoafo, R Mittal, A Eshraghi, Y Omidi… - Journal of Drug Delivery …, 2023 - Elsevier
Thiolated polymers, or thiomers, are a class of polymers that exhibit unique mucoadhesive
properties, allowing them to form strong covalent bonds with cysteine-rich subdomains of …

Challenges and Opportunities in the Oral Delivery of Recombinant Biologics

S Masloh, M Culot, F Gosselet, A Chevrel, L Scapozza… - Pharmaceutics, 2023 - mdpi.com
Recombinant biological molecules are at the cutting-edge of biomedical research thanks to
the significant progress made in biotechnology and a better understanding of subcellular …

Thiolation of arabinoxylan and its application in the fabrication of controlled release mucoadhesive oral films

M Hanif, M Zaman - DARU Journal of Pharmaceutical sciences, 2017 - Springer
Background Mucoadhesion is an important property that helps oral drug delivery system to
remain attached with buccal mucosa and hence to improve the delivery of the drug. The …

Thiolated polymers: pharmaceutical tool in nasal drug delivery of proteins and peptides

A Jain, P Hurkat, A Jain, A Jain, A Jain… - International journal of …, 2019 - Springer
Although bioavailability of peptides administered through nasal route is still under 1%
because of low membrane permeability, a short local residence time and a high metabolic …

In vitro and in vivo sustained release of exenatide from vesicular phospholipid gels for type II diabetes

Y Zhang, Y Zhong, M Hu, N Xiang, Y Fu… - Drug development …, 2016 - Taylor & Francis
Diabetes is a chronic disease that requires daily treatment to maintain a stable blood
glucose level. Sustained-release formulations can thus benefit the treatment of diabetes by …

Nasal delivery of high molecular weight drugs: recent trends and clinical evidence

E Kahraman, S Güngör, Y Özsoy - Nasal drug delivery: formulations …, 2023 - Springer
In recent years, the nasal route has been a promising administration for systemic drug
delivery. However, the nasal epithelial barrier hinders high molecular weight medications …

Novel Approaches for the Management of Type 2 Diabetes Mellitus: An Update

A Kumar, R Mazumder, A Rani… - Current Diabetes …, 2024 - ingentaconnect.com
Diabetes mellitus is an irreversible, chronic metabolic disorder indicated by hyperglycemia.
It is now considered a worldwide pandemic. T2DM, a spectrum of diseases initially caused …