Covering: 1988 to 2012 This review presents recommended nomenclature for the
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …

It was once widely held that nearly all reactions in biology were catalyzed via mechanisms
involving paired electron species. Beginning approximately 40 years ago, this paradigm was …

Streptococcal bacteria use peptide signals as a means of intraspecies communication.
These peptides can contain unusual post-translational modifications, providing opportunities …

The importance of methylthioadenosine/S‐adenosylhomocysteine (MTA/SAH) nucleosidase
in bacteria has started to be appreciated only in the past decade. A comprehensive analysis …

INTRODUCTION The microbes that live in and on our bodies (the human microbiome)
profoundly affect human health and disease. For example, within the lower gastrointestinal …

Protein and nucleic acid modification processes play a central role in cellular viability. These
range from the regulation of transcription via the modification of DNA, 1 the splicing of RNA …

S-Adenosylmethionine (SAM, also known as AdoMet) radical enzymes use SAM and a [4Fe-
4S] cluster to catalyze a diverse array of reactions. They adopt a partial triose-phosphate …

A subset of natural products, such as polyketides and nonribosomal peptides, is
biosynthesized while tethered to a carrier peptide via a thioester linkage. Recently, we …

Data mining methods in bioinformatics and comparative genomics commonly rely on
working definitions of protein families from prior computation. Partial phylogenetic profiling …

Ribosomally-synthesized and post-translationally modified peptides (RiPPs) are a large and
diverse family of natural products. They possess interesting biological properties such as …