Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases

SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

Brown adipose tissue and its role in insulin and glucose homeostasis

K Maliszewska, A Kretowski - International journal of molecular sciences, 2021 - mdpi.com
The increased worldwide prevalence of obesity, insulin resistance, and their related
metabolic complications have prompted the scientific world to search for new possibilities to …

Human brown adipose tissue and metabolic health: potential for therapeutic avenues

R Singh, A Barrios, G Dirakvand, S Pervin - Cells, 2021 - mdpi.com
Obesity-associated metabolic abnormalities comprise a cluster of conditions including
dyslipidemia, insulin resistance, diabetes and cardiovascular diseases that has affected …

Proanthocyanidins and where to find them: A meta-analytic approach to investigate their chemistry, biosynthesis, distribution, and effect on human health

G Mannino, G Chinigò, G Serio, T Genova, C Gentile… - Antioxidants, 2021 - mdpi.com
Proanthocyanidins (PACs) are a class of polyphenolic compounds that are attracting
considerable interest in the nutraceutical field due to their potential health benefits …

Inflammatory signaling and brown fat activity

F Omran, M Christian - Frontiers in Endocrinology, 2020 - frontiersin.org
Obesity is characterized by a state of chronic inflammation in adipose tissue mediated by the
secretion of a range of inflammatory cytokines. In comparison to WAT, relatively little is …

Brown adipose tissue transplantation as a novel alternative to obesity treatment: a systematic review

M Payab, M Abedi, N Foroughi Heravani… - International Journal of …, 2021 - nature.com
Background Obesity, a global challenge, is a complex disorder linked to various diseases.
Different kinds of treatments are currently used to treat or control this pandemic. Despite their …

[HTML][HTML] Effects of grape seed proanthocyanidin extract on obesity

M Liu, P Yun, Y Hu, J Yang, RB Khadka, X Peng - Obesity Facts, 2020 - karger.com
Obesity is a chronic metabolic disease resulting from excessive fat accumulation and/or
abnormal distribution caused by multiple factors. As a major component of metabolic …

PRDM16 regulating adipocyte transformation and thermogenesis: a promising therapeutic target for obesity and diabetes

N Jiang, M Yang, Y Han, H Zhao, L Sun - Frontiers in pharmacology, 2022 - frontiersin.org
Given that obesity and diabetes have been major public health concerns and that disease
morbidities have been rising continuously, effective treatment for these diseases is urgently …

Metabolic changes in female rats exposed to intrauterine hyperglycemia and postweaning consumption of high-fat diet

VG Paula, YK Sinzato… - Biology of …, 2022 - academic.oup.com
We evaluated the influence of the hyperglycemic intrauterine environment and postweaning
consumption of a high-fat diet (HFD) on the glycemia, insulin, lipid, and immunological …

The interplay between angiopoietin-like proteins and adipose tissue: another piece of the relationship between adiposopathy and cardiometabolic diseases?

S Bini, L D'Erasmo, A Di Costanzo, I Minicocci… - International Journal of …, 2021 - mdpi.com
Angiopoietin-like proteins, namely ANGPTL3-4-8, are known as regulators of lipid
metabolism. However, recent evidence points towards their involvement in the regulation of …