Exploiting the folate receptor α in oncology
Folate receptor α (FRα) came into focus as an anticancer target many decades after the
successful development of drugs targeting intracellular folate metabolism, such as …
successful development of drugs targeting intracellular folate metabolism, such as …
Advances in lung cancer treatment using nanomedicines
A Sharma, D Shambhwani, S Pandey, J Singh… - ACS …, 2022 - ACS Publications
Carcinoma of the lungs is among the most menacing forms of malignancy and has a poor
prognosis, with a low overall survival rate due to delayed detection and ineffectiveness of …
prognosis, with a low overall survival rate due to delayed detection and ineffectiveness of …
Beyond the margins: real-time detection of cancer using targeted fluorophores
RR Zhang, AB Schroeder, JJ Grudzinski… - Nature reviews Clinical …, 2017 - nature.com
Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …
revolution in which a range of biomedical applications are now benefiting from fluorescence …
[HTML][HTML] Targeting folate receptor alpha for cancer treatment
Promising targeted treatments and immunotherapy strategies in oncology and
advancements in our understanding of molecular pathways that underpin cancer …
advancements in our understanding of molecular pathways that underpin cancer …
CAR-T cell therapy in triple-negative breast cancer: Hunting the invisible devil
F Nasiri, M Kazemi, SMJ Mirarefin… - Frontiers in …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is known as the most intricate and hard-to-treat
subtype of breast cancer. TNBC cells do not express the well-known estrogen receptor …
subtype of breast cancer. TNBC cells do not express the well-known estrogen receptor …
Dye-doped silica nanoparticles: synthesis, surface chemistry and bioapplications
V Gubala, G Giovannini, F Kunc, MP Monopoli… - Cancer …, 2020 - Springer
Background Fluorescent silica nanoparticles have been extensively utilised in a broad
range of biological applications and are facilitated by their predictable, well-understood …
range of biological applications and are facilitated by their predictable, well-understood …
Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes
Background Survival rates for ovarian cancer remain poor, and monitoring and prediction of
therapeutic response may benefit from additional markers. Ovarian cancers frequently …
therapeutic response may benefit from additional markers. Ovarian cancers frequently …
Folic acid-functionalized, condensed magnetic nanoparticles for targeted delivery of doxorubicin to tumor cancer cells overexpressing the folate receptor
A Angelopoulou, A Kolokithas-Ntoukas, C Fytas… - ACS …, 2019 - ACS Publications
This study concerns the development of folic acid (FA)-functionalized iron oxide condensed
colloidal magnetic clusters for a more selective delivery of doxorubicin (DOX) to tumor …
colloidal magnetic clusters for a more selective delivery of doxorubicin (DOX) to tumor …
Cancer vaccines for triple-negative breast cancer: a systematic review
Triple-negative breast cancer (TNBC) is the subtype of breast cancer with the poorest
outcomes, and is associated with a high risk of relapse and metastasis. The treatment …
outcomes, and is associated with a high risk of relapse and metastasis. The treatment …
Anticancer nanotherapeutics in clinical trials: The work behind clinical translation of nanomedicine
A Parodi, EP Kolesova, MV Voronina… - International Journal of …, 2022 - mdpi.com
The ultimate goal of nanomedicine has always been the generation of translational
technologies that can ameliorate current therapies. Cancer disease represented the primary …
technologies that can ameliorate current therapies. Cancer disease represented the primary …