Gut microbiota metabolites and risk of major adverse cardiovascular disease events and death: a systematic review and meta‐analysis of prospective studies
Background Gut microbial metabolites have been implicated as novel risk factors for
cardiovascular events and premature death. The strength and consistency of associations …
cardiovascular events and premature death. The strength and consistency of associations …
Microbial modulation of cardiovascular disease
JM Brown, SL Hazen - Nature Reviews Microbiology, 2018 - nature.com
Although diet has long been known to contribute to the pathogenesis of cardiovascular
disease (CVD), research over the past decade has revealed an unexpected interplay …
disease (CVD), research over the past decade has revealed an unexpected interplay …
Role of gut microbiota and their metabolites on atherosclerosis, hypertension and human blood platelet function: a review
AK Duttaroy - Nutrients, 2021 - mdpi.com
Emerging data have demonstrated a strong association between the gut microbiota and the
development of cardiovascular disease (CVD) risk factors such as atherosclerosis …
development of cardiovascular disease (CVD) risk factors such as atherosclerosis …
Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors
Aims Systemic levels of trimethylamine N-oxide (TMAO), a pro-atherogenic and pro-
thrombotic metabolite produced from gut microbiota metabolism of dietary trimethylamine …
thrombotic metabolite produced from gut microbiota metabolism of dietary trimethylamine …
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease
Trimethylamine N-oxide (TMAO) is a biologically active molecule and is a putative promoter
of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its …
of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its …
The role of gut microbiota in atherosclerosis and hypertension
J Ma, H Li - Frontiers in pharmacology, 2018 - frontiersin.org
In recent years, accumulating evidence has indicated the importance of gut microbiota in
maintaining human health. Gut dysbiosis is associated with the pathogenesis of a number of …
maintaining human health. Gut dysbiosis is associated with the pathogenesis of a number of …
Serum trimethylamine N-oxide concentration is positively associated with first stroke in hypertensive patients
J Nie, L Xie, B Zhao, Y Li, B Qiu, F Zhu, G Li, M He… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Trimethylamine N-oxide (TMAO)—a gut derived metabolite—
has been shown to be atherogenic. It remains unknown whether TMAO is associated with …
has been shown to be atherogenic. It remains unknown whether TMAO is associated with …
Gut-derived metabolite, trimethylamine-N-oxide (TMAO) in cardio-metabolic diseases: detection, mechanism, and potential therapeutics
Trimethylamine N-oxide (TMAO) is a biologically active gut microbiome-derived dietary
metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely …
metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely …
Trimethylamine N‐oxide: breathe new life
S Subramaniam, C Fletcher - British Journal of Pharmacology, 2018 - Wiley Online Library
Association between elevated levels of systemic trimethylamine N‐oxide (TMAO) and
increased risk for adverse cardiovascular events have been proposed in recent years …
increased risk for adverse cardiovascular events have been proposed in recent years …
The gut microbiota-artery axis: A bridge between dietary lipids and atherosclerosis?
Atherosclerotic cardiovascular disease is one of the major leading global causes of death.
Growing evidence has demonstrated that gut microbiota (GM) and its metabolites play a …
Growing evidence has demonstrated that gut microbiota (GM) and its metabolites play a …