The innate immune system is the only defence weapon of invertebrates and a fundamental
defence mechanism of fish. The innate system also plays an instructive role in the acquired …

Premature ovarian failure (POF) is a heterogeneous syndrome with several causative
factors. Autoimmune mechanisms are involved in pathogenesis of 4-30% of POF cases. The …

ABSTRACT Mycograb (Neu Tec Pharma plc) is a human genetically recombinant antibody
against fungal heat shock protein 90 (HSP90). Antibody to HSP90 is closely associated with …

This review summarizes the complex role of heat-shock proteins (Hsp) in immune reactions,
especially the cellular effects of heat-shock proteins during the recognition processes by …

OBJECTIVE: To identify ovarian autoantigens associated with ovarian autoantibodies.
DESIGN: Hypothesis-generating prospective study. SETTING: Urban infertility referral …

The production of homozygous pigs with a disruption in the GGTA1 gene, which encodes
α1, 3galactosyltransferase (α1, 3GT), represented a critical step toward the clinical reality of …

Natural antibodies are present in the serum of vertebrates regardless of antigenic
stimulation. Characteristic activity is commonly detected against haptenated proteins, single …

After a long period of spermatogenesis (several weeks to months), marine fish spermatozoa
are delivered at male spawning in seawater (SW) at the same time as ova. In some fish …

Dilated cardiomyopathy (DCM) is a myocardial disease characterized by progressive
depression of myocardial contractile function and ventricular dilatation. Thirty percent of …

Heat shock proteins (HSPs) are components of a physiologic stress response that are also
over-expressed in various cancers including non-small cell lung cancer (NSCLC). During …