Neurovascular coupling reflects the close temporal and regional linkage between neural
activity and cerebral blood flow. Although providing mechanistic insight, our understanding …

Regulation of the cerebral circulation relies on the complex interplay between
cardiovascular, respiratory, and neural physiology. In health, these physiologic systems act …

BACKGROUND Intracranial pressure (ICP) is a clinically important variable after severe
traumatic brain injury (TBI) and has been monitored, along with clinical outcome, for over 25 …

Objectives: In severe traumatic brain injury, cerebral perfusion pressure management based
on cerebrovascular pressure reactivity index has the potential to provide a personalized …

Traumatic brain injury (TBI) is a common disorder with high morbidity and mortality,
accounting for one in every three deaths due to injury. Older adults are especially …

In December 2019, an outbreak of illness caused by a novel coronavirus (2019-nCoV,
subsequently renamed SARS-CoV-2) was reported in Wuhan, China. Coronavirus disease …

Impaired cerebrovascular reactivity in adult moderate and severe traumatic brain injury (TBI)
is known to be associated with worse global outcome at 6–12 months. As technology has …

Background Both intracranial pressure (ICP) and the cerebrovascular pressure reactivity
represent the dysregulation of pathways directly involved in traumatic brain injury (TBI) …

Cerebral multimodality monitoring (MMM) is, even with a general lack of Class I evidence,
increasingly recognized as a tool to support clinical decision-making in the neuroscience …

Neurointensive care (NIC) has contributed to great improvements in clinical outcomes for
patients with severe traumatic brain injury (TBI) by preventing, detecting, and treating …