Isolated ACTH deficiency induced by cancer immunotherapy: a systematic review

P Iglesias, JC Sánchez, JJ Díez - Pituitary, 2021 - Springer
Immunotherapy with immune checkpoint inhibitor (ICI) monoclonal antibodies has shown to
be an effective therapeutic alternative in several malignant tumors. However, adverse effects …

Isolated autoimmune adrenocorticotropic hormone deficiency: from a rare disease to the dominant cause of adrenal insufficiency related to check point inhibitors

R Percik, G Shlomai, A Tirosh, A Tirosh… - Autoimmunity …, 2020 - Elsevier
Objective Immune checkpoint inhibitors have introduced a new and heterogeneous class of
immune-related adverse effects, with the endocrine system being a predominant target for …

Hypophysitis secondary to nivolumab and pembrolizumab is a clinical entity distinct from ipilimumab-associated hypophysitis

A Faje, K Reynolds, L Zubiri, D Lawrence… - European journal of …, 2019 - academic.oup.com
Objective Little has been published describing hypophysitis after nivolumab or
pembrolizumab treatment. We aimed to (i) assess the risk of hypophysitis following …

Management of immune-related adverse events in endocrine organs induced by immune checkpoint inhibitors: clinical guidelines of the Japan Endocrine Society

H Arima, S Iwama, H Inaba, H Ariyasu, N Makita… - Endocrine …, 2019 - jstage.jst.go.jp
Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced
malignancies. However, these drugs can induce immune-related adverse events (irAEs) in …

Analysis of immune‐related adverse events caused by immune checkpoint inhibitors using the Japanese Adverse Drug Event Report database

S Hasegawa, H Ikesue, S Nakao… - … and drug safety, 2020 - Wiley Online Library
Purpose The aim of our study was to characterize the clinical features of immune‐related
adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs) in a real‐world …

Adrenal insufficiency related to anti-programmed death-1 therapy

R Ariyasu, A Horiike, T Yoshizawa, Y Dotsu… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Adrenal insufficiency is one of the adverse events (AEs) associated with
anti-programmed death-1 (PD1) therapy. Delaying diagnoses can lead to serious …

Primary hypothyroidism and isolated ACTH deficiency induced by nivolumab therapy: case report and review

MF Zeng, LL Chen, HY Ye, W Gong, LN Zhou, YM Li… - Medicine, 2017 - journals.lww.com
Interventions: Hormone replacements with levothyroxine and acetate cortisone were given
orally. Nivolumab was adjusted to lower dose and longer interval. Outcomes: The patient felt …

Hyponatremia and cancer: from bedside to benchside

B Fibbi, G Marroncini, L Naldi, C Anceschi, A Errico… - Cancers, 2023 - mdpi.com
Simple Summary This review article is focused on hyponatremia in cancer patients.
Hyponatremia is the most common electrolyte disorder in these patients and there is …

[HTML][HTML] Clinical characteristics, management, and potential biomarkers of endocrine dysfunction induced by immune checkpoint inhibitors

S Iwama, T Kobayashi, H Arima - Endocrinology and …, 2021 - synapse.koreamed.org
Immune-related adverse events (irAEs) affecting the endocrine glands are among the most
frequent irAEs induced by immune checkpoint inhibitors (ICIs) and include hypopituitarism …

Isolated adrenocorticotropic hormone deficiency and thyroiditis associated with nivolumab therapy in a patient with advanced lung adenocarcinoma: a case report and …

N Ohara, M Kobayashi, K Ohashi, R Ito, Y Ikeda… - Journal of medical case …, 2019 - Springer
Introduction Immune checkpoint inhibitors are a promising class of anticancer drugs. The
clinical benefits afforded by immune checkpoint inhibitors can be accompanied by immune …