Heparin-induced thrombocytopenia (HIT) is an immune complication of heparin therapy
caused by antibodies to complexes of platelet factor 4 (PF4) and heparin. Pathogenic …

Classically, platelets have been described as the cellular blood component that mediates
hemostasis and thrombosis. This important platelet function has received significant …

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet serious adverse
effect of the adenoviral vector vaccines ChAdOx1 nCoV-19 (AstraZeneca) and Ad26. COV2 …

Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to
heparins, characterized by thrombocytopenia and often severe thrombosis with high …

Mouse and human FcRs have been a major focus of attention not only of the scientific
community, through the cloning and characterization of novel receptors, and of the medical …

Upon blood vessel injury, platelets are exposed to adhesive proteins in the vascular wall
and soluble agonists, which initiate platelet activation, leading to formation of hemostatic …

Heparin-induced thrombocytopenia (HIT) is a life and limb-threatening complication of
heparin exposure. Here, we review the pathogenesis, incidence, diagnosis, and …

There is a growing appreciation for the contribution of platelets to immunity; however, our
knowledge mostly relies on platelet functions associated with vascular injury and the …

Heparin-induced thrombocytopenia is an immune-mediated disorder caused by antibodies
that recognize complexes of platelet factor 4 and heparin. Thrombosis is a central and …

Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are
based on a range of novel platforms, with adenovirus-based approaches (like ChAdOx1 …