Acute-on-chronic liver failure (ACLF) is a syndrome characterised by acute decompensation
of chronic liver disease associated with organ failures and high short-term mortality. Alcohol …

The term cirrhosis-associated immune dysfunction refers to the main syndromic
abnormalities of immune function, immunodeficiency and systemic inflammation that are …

Bacterial infection is a frequent trigger of acute-on-chronic liver failure (ACLF), syndrome
that could also increase the risk of infection. This investigation evaluated prevalence and …

The peripheral arterial vasodilation hypothesis has been most influential in the field of
cirrhosis and its complications. It has given rise to hundreds of pathophysiological studies in …

The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and
North America, the term is generally applied according to the European Association for the …

Bacterial infections are very common and represent one of the most important reasons of
progression of liver failure, development of liver-related complications, and mortality in …

Acute-on-chronic liver failure (ACLF) is a recently recognized syndrome characterized by
acute decompensation (AD) of cirrhosis and organ/system failure (s)(organ failure: liver …

The splicing factor SF3B1 is the most commonly mutated gene in the myelodysplastic
syndrome (MDS), particularly in patients with refractory anemia with ring sideroblasts …

Infections, due to a dysfunctional immune response, pose a great risk to patients with
decompensated cirrhosis and herald the beginning of the terminal phase of this disease …

Alcohol-related liver disease (ALD) remains the most important cause of death due to
alcohol. Infections, particularly bacterial infections, are one of the most frequent and severe …