The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

Colorectal cancer (CRC) therapy using conventional chemotherapeutics represents a
considerable burden for the patient's organism because of high toxicity while the response is …

The generation of reactive oxygen species (ROS) and an altered redox status are common
biochemical aspects in cancer cells. ROS can react with the polyunsaturated fatty acids of …

Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …

Chemoresistance is a central cause for the tumor management failure. Cancer cells disrupt
the redox homeostasis through reactive oxygen species (ROS) regulatory mechanisms …

The signal transducer and activator of transcription (STAT) proteins have important roles in
biological processes. The abnormal activation of STAT signalling pathways is also …

Colorectal cancer (CRC) is the third most common cancer and one of the main causes of
cancer death entire the world. Environmental, dietary, and lifestyle factors including red meat …

Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …

Piceatannol (PIC) is known to have anticancer activity, which has been attributed to its ability
to block the proliferation of cancer cells via suppression of the NF-kB signaling pathway …

Colorectal cancer (CRC) is one of the deadliest diseases worldwide due to a lack of early
detection methods and appropriate drug delivery strategies. Conventional imaging …