[HTML][HTML] Organoid and spheroid tumor models: techniques and applications
S Gunti, ATK Hoke, KP Vu, NR London Jr - Cancers, 2021 - mdpi.com
Simple Summary Cell cultures can be carried out in three dimensions (3D). Organoids and
spheroids are different 3D cell culture models that can be cultured with different techniques …
spheroids are different 3D cell culture models that can be cultured with different techniques …
[HTML][HTML] Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses
LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …
shown the therapeutic potential effect of MSC or their derived products. However, the …
[HTML][HTML] Large-scale perfused tissues via synthetic 3D soft microfluidics
S Grebenyuk, AR Abdel Fattah, M Kumar… - Nature …, 2023 - nature.com
The vascularization of engineered tissues and organoids has remained a major unresolved
challenge in regenerative medicine. While multiple approaches have been developed to …
challenge in regenerative medicine. While multiple approaches have been developed to …
[HTML][HTML] AI-enabled organoids: construction, analysis, and application
L Bai, Y Wu, G Li, W Zhang, H Zhang, J Su - Bioactive Materials, 2024 - Elsevier
Organoids, miniature and simplified in vitro model systems that mimic the structure and
function of organs, have attracted considerable interest due to their promising applications in …
function of organs, have attracted considerable interest due to their promising applications in …
Microfluidics for drug development: from synthesis to evaluation
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …
delivery, and drug evaluation. Compared with conventional drug development procedures …
[HTML][HTML] Promising applications of tumor spheroids and organoids for personalized medicine
Simple Summary Presently, the investigation of the tumor is carried out using different
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
In vitro strategies to vascularize 3D physiologically relevant models
A Dellaquila, C Le Bao, D Letourneur… - Advanced …, 2021 - Wiley Online Library
Vascularization of 3D models represents a major challenge of tissue engineering and a key
prerequisite for their clinical and industrial application. The use of prevascularized models …
prerequisite for their clinical and industrial application. The use of prevascularized models …
Mucuna pruriens in Parkinson's and in some other diseases: recent advancement and future prospective
Mucuna pruriens (Mp) is an annual and perennial legume which belongs to the family
Fabaceae having different types of therapeutic activity. Anti-oxidative, anti-inflammatory, anti …
Fabaceae having different types of therapeutic activity. Anti-oxidative, anti-inflammatory, anti …
Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids
Epithelial organoids derived from human donor tissues are important tools in fields ranging
from regenerative medicine to drug discovery. Organoid culture requires expansion of …
from regenerative medicine to drug discovery. Organoid culture requires expansion of …
Recent advances in organoid development and applications in disease modeling
An improved understanding of stem cell niches, organogenesis, and disease models has
paved the way for developing a three-dimensional (3D) organoid culture system. Organoid …
paved the way for developing a three-dimensional (3D) organoid culture system. Organoid …