[HTML][HTML] Medicinal uses, pharmacological activities, phytochemistry, and the molecular mechanisms of Punica granatum L.(pomegranate) plant extracts: A review

N Maphetu, JO Unuofin, NP Masuku, C Olisah… - Biomedicine & …, 2022 - Elsevier
Punica granatum L (pomegranate) is one of the Mediterranean medicinal plants that has
been used for generations in treating ulcers, diarrhea, and male infertility. Increasing …

[HTML][HTML] Treatment of liver fibrosis: Past, current, and future

CY Zhang, S Liu, M Yang - World Journal of Hepatology, 2023 - ncbi.nlm.nih.gov
Liver fibrosis accompanies the progression of chronic liver diseases independent of
etiologies, such as hepatitis viral infection, alcohol consumption, and metabolic-associated …

[HTML][HTML] Anti-angiogenic effects of natural compounds in diet-associated hepatic inflammation

S Novi, V Vestuto, P Campiglia, N Tecce, A Bertamino… - Nutrients, 2023 - mdpi.com
Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are the most
common causes of chronic liver disease and are increasingly emerging as a global health …

[HTML][HTML] Cyanidin Alleviated CCl4-Induced Acute Liver Injury by Regulating the Nrf2 and NF-κB Signaling Pathways

B Wang, S Cui, B Mao, Q Zhang, F Tian, J Zhao… - Antioxidants, 2022 - mdpi.com
Acute liver injury has multiple causes and can result in liver failure. In this study, we
evaluated the hepatoprotective ability of cyanidin (Cy) and investigated its associated …

[HTML][HTML] Effects of anthraquinones on immune responses and inflammatory diseases

D Xin, H Li, S Zhou, H Zhong, W Pu - Molecules, 2022 - mdpi.com
The anthraquinones (AQs) and derivatives are widely distributed in nature, including plants,
fungi, and insects, with effects of anti-inflammation and anti-oxidation, antibacterial and …

Nicotinic acid attenuates experimental non-alcoholic steatohepatitis by inhibiting the NLRP3 inflammasome/pyroptosis pathway

I Cardoso-Lezama, MÁ Fuentes-Figueroa… - Biochemical …, 2023 - Elsevier
Non-alcoholic steatohepatitis (NASH) is a global public health concern that may progress
into fibrosis, cirrhosis, and liver cancer, with limited curative treatment options. While the …

[HTML][HTML] An Overview of the Role of Peroxisome Proliferator-activated Receptors in Liver Diseases

Z Changizi, F Kajbaf, A Moslehi - Journal of Clinical and …, 2023 - ncbi.nlm.nih.gov
Peroxisome proliferator-activated receptors (PPARs) are a superfamily of nuclear
transcription receptors, consisting of PPARα, PPARγ, and PPARβ/δ, which are highly …

Banana peel ameliorated hepato-renal damage and exerted anti-inflammatory and anti-apoptotic effects in metal mixture mediated hepatic nephropathy by activation …

BF Eddie-Amadi, AN Ezejiofor, CN Orish… - Food and Chemical …, 2022 - Elsevier
This study evaluated the protective role of banana peel extract (BP) on heavy metal mixture
(HMM) mediated hepatorenal toxicity using a rat model. Twenty-five female Wistar albino …

The application of proteomics and metabolomics to reveal the molecular mechanism of Nutmeg-5 in ameliorating cardiac fibrosis following myocardial infarction

T Yan, X Zhu, X Zhang, X Jia, J Liu, X Wang, Y Xiao… - Phytomedicine, 2022 - Elsevier
Background Nutmeg-5, an ancient and classic formula in traditional Mongolian medicine
comprising five kinds of traditional Chinese medicine, is widely used in the treatment of …

New perspectives on Chinese medicine in treating hepatic fibrosis: Lipid droplets in hepatic stellate cells

C Shao, H Xu, X Sun, Y Huang, W Guo… - The American journal …, 2023 - World Scientific
Hepatic fibrosis (HF) is a wound healing response featuring excessive deposition of the
extracellular matrix (ECM) and activation of hepatic stellate cells (HSCs) that occurs during …