A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools

AT Pezacki, RL Gonciarz, T Okamura… - Proceedings of the …, 2024 - pnas.org
Iron is an essential element for life owing to its ability to participate in a diverse array of
oxidation–reduction reactions. However, misregulation of iron-dependent redox cycling can …

In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin

RL Gonciarz, H Jiang, L Tram, CL Hugelshofer… - Cell Chemical …, 2023 - cell.com
Dysregulated iron homeostasis underlies diverse pathologies, from ischemia-reperfusion
injury to epithelial-mesenchymal transition and drug-tolerant" persister" cancer cell states …

[HTML][HTML] Assessing the Potential of Small Peptides for Altering Expression Levels of the Iron-Regulatory Genes FTH1 and TFRC and Enhancing Androgen Receptor …

C Currie, C Bjerknes, TÅ Myklebust… - International Journal of …, 2023 - mdpi.com
Recent research highlights the key role of iron dyshomeostasis in the pathogenesis of
prostate cancer (PCa). PCa cells are heavily dependent on bioavailable iron, which …