Vimentin: Regulation and pathogenesis

D Paulin, A Lilienbaum, S Kardjian, O Agbulut, Z Li - Biochimie, 2022 - Elsevier
Vimentin, an abundant cytoplasmic intermediate filament protein, is recognized for its
important role in stabilizing intracellular structure. Vimentin has been recognized for its …

Plant molecular farming of virus‐like nanoparticles as vaccines and reagents

EP Rybicki - Wiley Interdisciplinary Reviews: Nanomedicine …, 2020 - Wiley Online Library
The use of plants for the production of virus‐like nanoparticles (VNPs) dates back to
separating natural empty capsids of plant viruses from whole virions nearly 70 years ago …

TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops

J Zhang, XJ Tian, H Zhang, Y Teng, R Li, F Bai… - Science …, 2014 - science.org
The process of epithelial-to-mesenchymal transition (EMT) is an essential type of cellular
plasticity associated with a change from epithelial cells that function as a barrier consisting …

Virus-based nanoparticles as versatile nanomachines

KJ Koudelka, AS Pitek, M Manchester… - Annual review of …, 2015 - annualreviews.org
Nanoscale engineering is revolutionizing the way we prevent, detect, and treat diseases.
Viruses have played a special role in these developments because they can function as …

Vimentin as a potential target for diverse nervous system diseases

KZ Chen, SX Liu, YW Li, T He, J Zhao… - Neural regeneration …, 2023 - journals.lww.com
Vimentin is a major type III intermediate filament protein that plays important roles in several
basic cellular functions including cell migration, proliferation, and division. Although vimentin …

Mechanical and non‐mechanical functions of filamentous and non‐filamentous vimentin

AE Patteson, A Vahabikashi, RD Goldman… - …, 2020 - Wiley Online Library
Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …

Targeting vimentin: A multifaceted approach to combatting cancer metastasis and drug resistance

A Tabatabaee, B Nafari, A Farhang, A Hariri… - Cancer and Metastasis …, 2024 - Springer
This comprehensive review explores vimentin as a pivotal therapeutic target in cancer
treatment, with a primary focus on mitigating metastasis and overcoming drug resistance …

Vimentin takes a hike–Emerging roles of extracellular vimentin in cancer and wound healing

S Parvanian, LS Coelho-Rato, AE Patteson… - Current Opinion in Cell …, 2023 - Elsevier
Vimentin is a cytoskeletal protein important for many cellular processes, including
proliferation, migration, invasion, stress resistance, signaling, and many more. The vimentin …

Cell surface detection of vimentin, ACE2 and SARS-CoV-2 Spike proteins reveals selective colocalization at primary cilia

V Lalioti, S González-Sanz, I Lois-Bermejo… - Scientific reports, 2022 - nature.com
Abstract The SARS-CoV-2 Spike protein mediates docking of the virus onto cells prior to
viral invasion. Several cellular receptors facilitate SARS-CoV-2 Spike docking at the cell …

The pharmacology of plant virus nanoparticles

CI Nkanga, NF Steinmetz - Virology, 2021 - Elsevier
The application of nanoparticles for medical purposes has made enormous strides in
providing new solutions to health problems. The observation that plant virus-based …