Circular RNA (circRNA) can modulate the gene expression via sponging microRNA
(miRNA) in multiple malignancies. Nevertheless, the detailed function of circ_0001658 in …

Osteosarcoma is the most prevalent bone cancer, and chemotherapy is still an
indispensable treatment in its clinical practice. Cisplatin (CDDP) has become the most …

Lung cancer is the primary cause of cancer-related death worldwide, and development of
novel lung cancer preventive and therapeutic agents are urgently needed. Brassica nigra …

Background Pancreatic ductal adenocarcinoma is prone to metastasis, resulting in short
survival and low quality of life. LncRNAs are pivotal orchestrators that participate in various …

Background Osteosarcoma (OS) patients with lung metastasis have poor prognoses, and
effective therapeutic strategies for delaying or inhibiting the spread of lung metastasis from …

PAK4 and PD-L1 have been suggested as novel therapeutic targets in human cancers.
Moreover, PAK4 has been suggested to be a molecule closely related to the immune …

Ubiquitination, a multifaceted post-translational modification, regulates protein function,
degradation, and gene expression. The pivotal role of ubiquitination in the pathogenesis …

The ubiquitin–proteasome system (UPS) maintains intracellular protein homeostasis and
cellular function by regulating various biological processes. Ubiquitination, a common post …

Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Nevertheless,
the detailed molecular mechanisms of the progression of LUAD remain largely unknown …

Background Family with sequence similarity 83 members H (FAM83H) is one member of
Family with sequence similarity 83 (FAM83) family, which possess oncogenic properties in …