Fluid transport in the brain

MK Rasmussen, H Mestre… - Physiological …, 2022 - journals.physiology.org
The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

SW Bothwell, D Janigro, A Patabendige - Fluids and Barriers of the CNS, 2019 - Springer
The fine balance between the secretion, composition, volume and turnover of cerebrospinal
fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance …

The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

JL Mitchell, HS Lyons, JK Walker, A Yiangou, O Grech… - Brain, 2023 - academic.oup.com
Therapeutics to reduce intracranial pressure are an unmet need. Preclinical data have
demonstrated a novel strategy to lower intracranial pressure using glucagon-like peptide-1 …

European headache federation guideline on idiopathic intracranial hypertension

J Hoffmann, SP Mollan, K Paemeleire, C Lampl… - The journal of headache …, 2018 - Springer
Abstract Background Idiopathic Intracranial Hypertension (IIH) is characterized by an
elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely …

Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms

A Yiangou, SP Mollan, AJ Sinclair - Nature Reviews Neurology, 2023 - nature.com
The understanding of idiopathic intracranial hypertension (IIH) has evolved over the past few
years. Previously, IIH was considered a disease exclusively affecting the neuro-ophthalmic …

Multidisciplinary consensus guideline for the diagnosis and management of spontaneous intracranial hypotension

S Cheema, J Anderson, H Angus-Leppan… - Journal of Neurology …, 2023 - jnnp.bmj.com
Background We aimed to create a multidisciplinary consensus clinical guideline for best
practice in the diagnosis, investigation and management of spontaneous intracranial …

[HTML][HTML] A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

MW O'Reilly, CSJ Westgate, C Hornby, H Botfield… - JCI insight, 2019 - ncbi.nlm.nih.gov
Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, characterized by
elevated intracranial pressure frequently manifesting with chronic headaches and visual …

Headache attributed to idiopathic intracranial hypertension and persistent Post‐Idiopathic intracranial hypertension headache: a narrative review

SP Mollan, O Grech, AJ Sinclair - … The Journal of Head and Face …, 2021 - Wiley Online Library
Objective Headache is a near‐universal sequela of idiopathic intracranial hypertension (IIH).
The aim of this paper is to report current knowledge of headache in IIH and to identify …

The potentially modifiable risk factor in idiopathic intracranial hypertension: body weight

SP Mollan, AA Tahrani, AJ Sinclair - Neurology: Clinical Practice, 2021 - AAN Enterprises
Purpose of Review Idiopathic intracranial hypertension (IIH) prevalence increased in
conjunction with rising obesity rates. Here, we highlight the importance of weight …

Advances in the understanding of headache in idiopathic intracranial hypertension

SP Mollan, J Hoffmann, AJ Sinclair - Current opinion in neurology, 2019 - journals.lww.com
Advances in the understanding of headache in idiopathic intr... : Current Opinion in Neurology
Advances in the understanding of headache in idiopathic intracranial hypertension : Current …