USP28 facilitates pancreatic cancer progression through activation of Wnt/β-catenin pathway via stabilising FOXM1

L Chen, Z Xu, Q Li, Q Feng, C Zheng, Y Du… - Cell death & …, 2021 - nature.com
Ubiquitination is an important post-translational modification that can be reversed by a family
of enzymes called deubiquitinating enzymes (DUBs). Ubiquitin-specific protease 28 …

Ubiquitin-specific protease 28: the decipherment of its dual roles in cancer development

X Ren, M Jiang, P Ding, X Zhang, X Zhou… - … Hematology & Oncology, 2023 - Springer
As significant posttranslational modifications, ubiquitination and deubiquitination, whose
balance is modulated by ubiquitin-conjugating enzymes and deubiquitinating enzymes …

Recent advances in the development of deubiquitinases inhibitors as antitumor agents

LL Zheng, LT Wang, YW Pang, LP Sun, L Shi - European Journal of …, 2024 - Elsevier
Ubiquitination is a type of post-translational modification that covalently links ubiquitin to a
target protein, which plays a critical role in modulating protein activity, stability, and …

Deubiquitinating enzyme USP28 inhibitor AZ1 alone and in combination with cisplatin for the treatment of non-small cell lung cancer

Y Song, L Wang, Y Zheng, L Jia, C Li, K Chao, L Li… - Apoptosis, 2024 - Springer
Lung cancer is one of the most common malignant tumors. Despite decades of research, the
treatment of lung cancer remains challenging. Non-small cell lung cancer (NSCLC) is the …

[HTML][HTML] Comprehensive prognostic and immunological analysis of Ubiquitin Specific Peptidase 28 in pan-cancers and identification of its role in hepatocellular …

W Zhou, J Chen, J Wang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Ubiquitin Specific Peptidase 28 (USP28), as a member of the DUBs family, has
been reported to regulate the occurrence and development of some tumors, but its …

Long Non-coding RNA LINC01426 Contributes to the Malignant Behaviors of NSCLC Via Acting As a Sponge for miR-143-3p

W Liu, P Si, H Fang, G Ning, C Lu, Y Huang - Biochemical Genetics, 2022 - Springer
Recently, long non-coding RNA (lncRNA) is proved to play critical roles in non-small cell
lung cancer (NSCLC) progression. However, the detailed effects of LINC01426 in NSCLC …

The effect of krill oil on Wnt/β-catenin signaling pathway in acetaminophen-induced acute liver injury in mice

Y Şahin, AK Devrim, ME Alçığır, A Şenol… - Turkish Journal of …, 2023 - degruyter.com
Objectives This study investigated the effect of krill oil (KO) on liver damage caused by
acetaminophen (APAP). Methods In the present study, the control and APAP groups were …

Late effects of cutaneous 3-methylcholanthrene exposure on DNA damage-related pleiotropic growth factors and oxidative stress markers in mice.

D AK, B KK - Bratislava Medical Journal/Bratislavské …, 2020 - search.ebscohost.com
BACKGROUND: Skin is the body's fi rst defence against direct exposure to variety of
chemicals. Polycyclic aromatic hydrocarbons such as 3-methylcholanthrene (3-MC) are …

COMPREHENDING COVID-19: IMMUNOPATHOGENIC MECHANISMS OF CYTOKINE ACTION

E Akanbong, AK Devrim, A Şenol… - Medical Journal of …, 2021 - dergipark.org.tr
Cytokine release syndrome (CRS) or cytokine storm is as a result of the excess production of
pro-inflammatory cytokines which is due to the disproportionate response of the immune …