[HTML][HTML] Bioactive compounds from medicinal plants: Focus on Piper species

EE Mgbeahuruike, T Yrjönen, H Vuorela… - South African Journal of …, 2017 - Elsevier
This article reviews new discoveries related to the phytochemistry and biological activities of
bioactive compounds from Piper species. It outlines the anticancer, anti-parasitic, and …

Overview of the therapeutic potential of piplartine (piperlongumine)

DP Bezerra, C Pessoa, MO De Moraes… - European Journal of …, 2013 - Elsevier
Piplartine (piperlongumine, 5, 6-dihydro-1-[(2E)-1-oxo-3-(3, 4, 5-trimethoxyphenyl)-2-
propenyl]-2 (1H)-pyridinone) is a biologically active alkaloid/amide from peppers, as from …

[HTML][HTML] Alkaloids isolated from natural herbs as the anticancer agents

JJ Lu, JL Bao, XP Chen, M Huang… - … and alternative medicine …, 2012 - ncbi.nlm.nih.gov
Alkaloids are important chemical compounds that serve as a rich reservoir for drug
discovery. Several alkaloids isolated from natural herbs exhibit antiproliferation and …

[HTML][HTML] Piperine-a major principle of black pepper: a review of its bioactivity and studies

Z Stojanović-Radić, M Pejčić, M Dimitrijević, A Aleksić… - Applied Sciences, 2019 - mdpi.com
Piperine is the main compound present in black pepper, and is the carrier of its specific
pungent taste, which is responsible for centuries of human dietary utilization and worldwide …

[HTML][HTML] Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model

L Lai, Q Fu, Y Liu, K Jiang, Q Guo, Q Chen… - Acta Pharmacologica …, 2012 - nature.com
Aim: To investigate the effects of piperine, a major pungent alkaloid present in Piper nigrum
and Piper longum, on the tumor growth and metastasis of mouse 4T1 mammary carcinoma …

Piperlongumine (piplartine) as a lead compound for anticancer agents–Synthesis and properties of analogues: A mini-review

K Piska, A Gunia-Krzyżak, P Koczurkiewicz… - European journal of …, 2018 - Elsevier
Piperlongumine, also known as piplartine, is an amide alkaloid of Piper longum L.(long
piper), a medical plant known from Ayurvedic medicine. Although was discovered well over …

Mechanistic insight into immunomodulatory effects of food-functioned plant secondary metabolites

ASM Ali Reza, MS Nasrin, MA Hossen… - Critical reviews in …, 2023 - Taylor & Francis
Medicinally important plant-foods offer a balanced immune function, which is essential for
protecting the body against antigenic invasion, mainly by microorganisms …

Piperine: old spice and new nutraceutical?

K Smilkov, DG Ackova, A Cvetkovski… - Current …, 2019 - ingentaconnect.com
Background: Many of the activities associated with pepper fruits have been attributed to
piperine, the most active compound present in these spices. Objective: This paper aims to …

Antitumor properties of a sulfated polysaccharide from the red seaweed Champia feldmannii (Diaz‐Pifferer)

KOAL Lins, DP Bezerra, APNN Alves… - Journal of Applied …, 2009 - Wiley Online Library
In recent years, much attention has been focused on polysaccharides isolated from natural
sources. The aim of this study was to investigate the in vitro and in vivo antitumor properties …

[HTML][HTML] Piperine, a bioactive component of pepper spice exerts therapeutic effects on androgen dependent and androgen independent prostate cancer cells

A Samykutty, AV Shetty, G Dakshinamoorthy… - PLoS …, 2013 - journals.plos.org
Prostate cancer is the most common solid malignancy in men, with 32,000 deaths annually.
Piperine, a major alkaloid constituent of black pepper, has previously been reported to have …