The goal of this review is to briefly summarize the two primary pathways of hemostasis,
primary hemostasis and secondary hemostasis, as well as to summarize anticoagulant …

A quick literature search in the MEDLINE databases from 1966 to 1998 using the search
term disseminated intravascular coagulation (DIC) and related key words yields an …

Background Factor XI, a component of the intrinsic pathway of coagulation, contributes to the
generation of thrombin, which is involved in both the formation of fibrin and protection …

In the early 1960s, shortly after the introduction of oral contraceptives, the first case reports
appeared describing venous thrombosis and pulmonary emboli in women using this method …

When blood is exposed to negatively charged surface materials such as glass, an enzymatic
cascade known as the contact system becomes activated. This cascade is initiated by …

Recently, a new inhibitor of fibrinolysis was described, which downregulated fibrinolysis
after it was activated by thrombin, and was therefore named TAFI (thrombin-activatable …

Recently, a new inhibitor of fibrinolysis was described. This inhibitor downregulated
fibrinolysis after it was activated by thrombin, and was therefore named TAFI (thrombin …

Thrombin activatable fibrinolysis inhibitor (TAFI) is a carboxypeptidase B-like proenzyme,
that after activation down regulates fibrinolysis. TAFI is activated by thrombin in the presence …

The thrombin‐catalysed conversion of plasma fibrinogen into fibrin and the development of
an insoluble fibrin clot are the final steps of the coagulation cascade during haemostasis. A …

TAFI (thrombin activatable fibrinolysis inhibitor) down regulates fibrinolysis after activation by
relatively high concentrations of thrombin generated during coagulation via thrombin …