Tuning the ribosome: the influence of rRNA modification on eukaryotic ribosome biogenesis and function
KE Sloan, AS Warda, S Sharma, KD Entian… - RNA biology, 2017 - Taylor & Francis
ABSTRACT rRNAs are extensively modified during their transcription and subsequent
maturation in the nucleolus, nucleus and cytoplasm. RNA modifications, which are installed …
maturation in the nucleolus, nucleus and cytoplasm. RNA modifications, which are installed …
RNA pseudouridylation: new insights into an old modification
J Ge, YT Yu - Trends in biochemical sciences, 2013 - cell.com
Pseudouridine is the most abundant post-transcriptionally modified nucleotide in various
stable RNAs of all organisms. Pseudouridine is derived from uridine via base-specific …
stable RNAs of all organisms. Pseudouridine is derived from uridine via base-specific …
Engineered nucleic acids encoding a modified erythropoietin and their expression
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Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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RMDisease: a database of genetic variants that affect RNA modifications, with implications for epitranscriptome pathogenesis
Deciphering the biological impacts of millions of single nucleotide variants remains a major
challenge. Recent studies suggest that RNA modifications play versatile roles in essential …
challenge. Recent studies suggest that RNA modifications play versatile roles in essential …
Engineered nucleic acids and methods of use thereof
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
Modified polynucleotides for the production of biologics and proteins associated with human disease
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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Modified polynucleotides for the production of secreted proteins
T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
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In vivo production of proteins
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
[HTML][HTML] Extracellular vesicle-mediated export of fungal RNA
Extracellular vesicles (EVs) play an important role in the biology of various organisms,
including fungi, in which they are required for the trafficking of molecules across the cell wall …
including fungi, in which they are required for the trafficking of molecules across the cell wall …