Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …
strong resistance to therapy, leading to the poor prognosis in several cancer types …
New anti-cancer explorations based on metal ions
H Hu, Q Xu, Z Mo, X Hu, Q He, Z Zhang… - Journal of …, 2022 - Springer
Due to the urgent demand for more anti-cancer methods, the new applications of metal ions
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …
Chemical exchange saturation transfer (CEST): what is in a name and what isn't?
PCM Van Zijl, NN Yadav - Magnetic resonance in medicine, 2011 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging is a relatively new magnetic
resonance imaging contrast approach in which exogenous or endogenous compounds …
resonance imaging contrast approach in which exogenous or endogenous compounds …
Alternatives to gadolinium-based metal chelates for magnetic resonance imaging
Magnetic resonance imaging (MRI) has been immensely valuable in diagnostic clinical
imaging over the last few decades owing to its exceptional spatial and anatomical …
imaging over the last few decades owing to its exceptional spatial and anatomical …
Biomedical applications of macrocyclic ligand complexes
RE Mewis, SJ Archibald - Coordination Chemistry Reviews, 2010 - Elsevier
Macrocyclic chelators can form highly stable complexes with transition metals and
lanthanides. In this review, the recent advances towards biomedical applications of …
lanthanides. In this review, the recent advances towards biomedical applications of …
Gadolinium (III) complexes as MRI contrast agents: ligand design and properties of the complexes
P Hermann, J Kotek, V Kubíček, I Lukeš - Dalton Transactions, 2008 - pubs.rsc.org
Magnetic resonance imaging is a commonly used diagnostic method in medicinal practice
as well as in biological and preclinical research. Contrast agents (CAs), which are often …
as well as in biological and preclinical research. Contrast agents (CAs), which are often …
Chemical exchange saturation transfer contrast agents for magnetic resonance imaging
AD Sherry, M Woods - Annu. Rev. Biomed. Eng., 2008 - annualreviews.org
Magnetic resonance imaging (MRI) contrast agents have become an important tool in
clinical medicine. The most common agents are Gd3+-based complexes that shorten bulk …
clinical medicine. The most common agents are Gd3+-based complexes that shorten bulk …
A concentration‐independent method to measure exchange rates in PARACEST agents
The efficiency of chemical exchange dependent saturation transfer (CEST) agents is largely
determined by their water or proton exchange kinetics, yet methods to measure such …
determined by their water or proton exchange kinetics, yet methods to measure such …
Layer-by-layer capsules for magnetic resonance imaging and drug delivery
H Ai - Advanced drug delivery reviews, 2011 - Elsevier
Layer-by-layer (LbL) self-assembled polyelectrolyte capsules have demonstrated their
unique advantages and capability in drug delivery applications. These ordered micro/nano …
unique advantages and capability in drug delivery applications. These ordered micro/nano …