Bone morphogenetic protein-2 in development and bone homeostasis

D Halloran, HW Durbano, A Nohe - Journal of developmental biology, 2020 - mdpi.com
Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the
Transforming Growth Factor-Beta (TGF-β) superfamily. These proteins are essential to many …

[HTML][HTML] Selective estrogen receptor modulators (SERMs) and selective estrogen receptor degraders (SERDs) in cancer treatment

HK Patel, T Bihani - Pharmacology & therapeutics, 2018 - Elsevier
Breast cancer is the most frequently diagnosed cancer in women, with estrogen receptor
positive (ER+) breast cancer making up approximately 75% of all breast cancers diagnosed …

Genetic/familial high-risk assessment: breast, ovarian, and pancreatic, version 2.2021, NCCN clinical practice guidelines in oncology

MB Daly, T Pal, MP Berry, SS Buys, P Dickson… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and
Pancreatic focus primarily on assessment of pathogenic or likely pathogenic variants …

Cancer-associated venous thromboembolic disease, version 2.2021, NCCN clinical practice guidelines in oncology

MB Streiff, B Holmstrom, D Angelini, A Ashrani… - Journal of the National …, 2021 - jnccn.org
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Cancer-Associated
Venous Thromboembolic Disease focus on the prevention, diagnosis, and treatment of …

Drug repurposing in cancer

L Sleire, HE Førde, IA Netland, L Leiss, BS Skeie… - Pharmacological …, 2017 - Elsevier
Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …

Prevention and treatment of postmenopausal osteoporosis

SH Tella, JC Gallagher - The Journal of steroid biochemistry and molecular …, 2014 - Elsevier
In the beginning, that is from the 1960's, when a link between menopause and osteoporosis
was first identified; estrogen treatment was the standard for preventing bone loss, however …

Tamoxifen a pioneering drug: An update on the therapeutic potential of tamoxifen derivatives

I Ahmad - European journal of medicinal chemistry, 2018 - Elsevier
Abstract Tamoxifen (ICI 46 474), trans-1-(4-β-dimethylaminoethoxyphenyl)-1, 2-diphenylbut-
1-ene, is the most commonly used drug for the treatment of estrogen receptor positive breast …

[HTML][HTML] European guidance for the diagnosis and management of osteoporosis in postmenopausal women

JA Kanis, EV McCloskey, H Johansson… - Osteoporosis …, 2013 - Springer
European guidance for the diagnosis and management of osteoporosis in postmenopausal
women | Osteoporosis International Skip to main content SpringerLink Account Menu Find a …

European guidance for the diagnosis and management of osteoporosis in postmenopausal women

JA Kanis, C Cooper, R Rizzoli, JY Reginster… - Osteoporosis …, 2019 - Springer
Guidance is provided in a European setting on the assessment and treatment of
postmenopausal women at risk from fractures due to osteoporosis. Introduction The …

Tamoxifen: a most unlikely pioneering medicine

VC Jordan - Nature reviews Drug discovery, 2003 - nature.com
For more than 25 years, tamoxifen has been the gold standard for the endocrine treatment of
all stages of oestrogen-receptor-positive breast cancer, and the World Health Organization …