Introduction: Glycoproteomics is an important subdiscipline of proteomics, focusing on the
role of protein glycosylation in various biological processes. Protein glycosylation is the …

Growing significance of glycosylation in protein functions has accelerated the development
of methodologies for detection, identification, and characterization of protein glycosylation. In …

Glycosylation is one of the most common and important protein modifications in biological
systems. Many glycoproteins naturally occur at low abundances, which makes …

Disruption of the glycosylation machinery is a common feature in many types of cancer, and
colorectal cancer (CRC) is no exception. Core fucosylation is mediated by the enzyme …

Protein glycosylation is a crucial factor that must be evaluated in biological pharmaceuticals.
The glycoform profile of a protein can vary depending on the conditions of the cultivation …

The N-linked glycosylation of four lots of a marketed human therapeutic monoclonal
antibody (mAb) was assessed by three orthogonal chromatographic methods and a …

This study was performed to monitor the glycoform distribution of a recombinant antibody
fusion protein expressed in CHO cells over the course of fed-batch bioreactor runs using …

The Cordyceps militaris gene CCM_03832 encodes a ricin-B like lectin. The gene was
cloned and expressed in Escherichia coli, and its protein product, named CMRBL (C …

Lectin microarrays are increasingly used as screening tools with a high potential for
glycobiology analysis, providing a high-sensitivity profiling of complex glycan features in a …

Glycosylation is a critical parameter used to evaluate protein quality and consistency. N-
linked glycan profiling is fundamental to the support of biotherapeutic protein manufacturing …