We provide an overview of the basic concepts of scaling and dimensional analysis, followed
by a review of some of the recent work on applying these concepts to modeling instrumented …

The functional behaviour of articular cartilage in diarthrodial joints is determined by its
morphological and biomechanical properties. Whereas morphological changes are mainly …

OBJECTIVE: Substantial changes in articular cartilage composition and mechanical
properties occur during the development of osteoarthritis (OA). While softening in the initial …

Isotropic hyperelastic models have been used to determine the material properties of normal
human cartilage, but there remains an incomplete understanding of how these properties …

Load-bearing characteristics of articular cartilage are impaired during tissue degeneration.
Quantitative microscopy enables in vitro investigation of cartilage structure but determination …

Collagen fibrils of articular cartilage have specific depth-dependent orientations and the
fibrils bend in the cartilage surface to exhibit split-lines. Fibrillation of superficial collagen …

Musculoskeletal (MSK) ultrasound has well-established advantages, able to investigate very
small structures with high resolution and a quick and real-time dynamic evaluation with the …

Advances in computational mechanics, constitutive modeling, and techniques for subject-
specific modeling have opened the door to patient-specific simulation of the relationships …

Mechanical properties of articular cartilage are controlled by tissue composition and
structure. Cartilage function is sensitively altered during tissue degeneration, in osteoarthritis …

OBJECTIVE: Mechanical indentation and ultrasound (US) indentation instruments have
been introduced for quantitative assessment of cartilage properties in vivo. In this study, we …