Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

Hfq is an RNA-binding protein that is common to diverse bacterial lineages and has key
roles in the control of gene expression. By facilitating the pairing of small RNAs with their …

The molecular roles of many RNA‐binding proteins in bacterial post‐transcriptional gene
regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA …

Hfq is a ubiquitous, Sm‐like RNA binding protein found in most bacteria and some archaea.
Hfq binds small regulatory RNAs (sRNAs), facilitates base pairing between sRNAs and their …

Many bacteria use small RNA s (sRNA s) and the RNA chaperone Hfq to regulate mRNA
stability and translation. Hfq, a ring‐shaped homohexamer, has multiple faces that can bind …

A large group of bacterial small regulatory RNAs (sRNAs) use the Hfq chaperone to mediate
pairing with and regulation of mRNAs. Recent findings help to clarify how Hfq acts and …

Chemical probing is an important tool for characterizing the complex folded structures of
RNA molecules, many of which play key cellular roles. Electrophilic SHAPE reagents create …

Most of the sequenced bacterial genomes contain a gene encoding a protein known as Hfq
that resembles the eukaryotic RNA-binding proteins of the LSm family. It was originally …

The bacterial Sm protein and RNA chaperone Hfq stabilizes small noncoding RNAs
(sRNAs) and facilitates their annealing to mRNA targets involved in stress tolerance and …

The RNA chaperone protein Hfq is required for the function of all small RNAs (sRNAs) that
regulate mRNA stability or translation by limited base pairing in Escherichia coli. While there …