Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

Colorectal cancer (CRC) is the world's third most prevalent cancer and the main cause of
cancer-related mortality. A lot of work has been put into improving CRC patients' clinical …

Abstract Yes-associated protein 1 (YAP1) exerts significant effects in various malignancies.
However, the oncogenic role of YAP1 remains controversial, and the mechanism by which …

Acquired resistance to chemotherapy remains a major stumbling block in cancer treatment.
Chronic inflammation has a crucial role in induction of chemoresistance and results, in part …

The fields of applied and translational microRNA research have exploded in recent years as
microRNAs have been implicated across a spectrum of diseases. MicroRNA biomarkers …

Colorectal cancer (CRC) is a major cause of death worldwide. Novel non-invasive, high
diagnostic value screening test is urgently needed to improve survival rate, treatment and …

Highlights•Macrophage migration inhibitory factor (MIF) plays a crucial role in cancer and
inflammatory diseases.•Epigenetic mechanisms are involved in MIF-mediated …

Colorectal cancer (CRC) is one type of tumor with the highest frequency and mortality
worldwide. Although current treatments increase patient survival, it is important to detect …

While previous research on cancer biology has focused on genes that code for proteins, in
recent years it has been discovered that non-coding RNAs (ncRNAs) play key regulatory …

Background: Colorectal cancer (CRC) is one of the leading causes of death across the
globe. Early diagnosis with high sensitivity can prevent CRC progression, thereby reducing …