Since the discovery that baculoviruses can efficiently transduce mammalian cells,
baculoviruses have been extensively studied as potential vectors for both in vitro and in vivo …

The monopoly of insect cells to host baculovirus Autographa californica multiple nuclear
polyhedrosis virus (AcMNPV) as a eukaryotic gene expression system has been shattered …

The objective of a polymerase chain reaction (PCR) is to amplify a specific DNA segment
without any nonspecific by-products. In principle, each physical and chemical component of …

Baculoviruses are enveloped insect viruses that can carry large quantities of foreign DNA in
their genome. Baculoviruses have proved to be very promising gene therapy vectors but …

Application of viral vectors derived from human viruses to mediate immune response in
animals and humans has been greatly hampered by the problems associated with pre …

Pseudotyping of viral vectors has been widely used to enhance viral transduction efficiency.
One of the most popular pseudotyping proteins has been the G-protein of the Vesicular …

Tumor cells and vasculature offer specific targets for the selective delivery of therapeutic
genes. To achieve tumor-specific gene transfer, baculovirus tropism was manipulated by …

Various methods have been developed to transfer and express genes in mammalian cells.
Each method, whether virally, non-virally, or physically-based, has unique favorable …

Gene delivery into kidney cells is essential to the development of gene therapy for
nephropathy. This paper describes the use of baculovirus Autographa californica …

Baculoviruses can express transgenes in a wide range of vertebrate cells. However, in some
cells transgene expression is weak. To enhance transgene expression, we studied the effect …