Pattern separation and completion of distinct axonal inputs transmitted via micro-tunnels between co-cultured hippocampal dentate, CA3, CA1 and entorhinal cortex …

D Poli, BC Wheeler, TB DeMarse… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Functions ascribed to the hippocampal sub-regions for encoding episodic
memories include the separation of activity patterns propagated from the entorhinal cortex …

Sparse and specific coding during information transmission between co-cultured dentate gyrus and CA3 hippocampal networks

D Poli, S Thiagarajan, TB DeMarse… - Frontiers in neural …, 2017 - frontiersin.org
To better understand encoding and decoding of stimulus information in two specific
hippocampal sub-regions, we isolated and co-cultured rat primary dentate gyrus (DG) and …

Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies

R Greget, S Dadak, L Barbier, F Lauga… - Neurotoxicology, 2016 - Elsevier
Exposure to organophosphorus (OP) compounds, either pesticides or chemical warfare
agents, represents a major health problem. As potent irreversible inhibitors of …

MoS2 photonic synaptic device development for non-invasive detection of Parkinson's disease

P Divyashree, B Sharmila… - … Science and Technology, 2024 - iopscience.iop.org
The brain-inspired computation using synaptic devices has opened a new avenue for
neuromorphic intelligent systems. This paper presents the development of a MoS 2 based …

Synaptic efficacy as a function of ionotropic receptor distribution: a computational study

SL Allam, JMC Bouteiller, EY Hu, N Ambert, R Greget… - PLoS …, 2015 - journals.plos.org
Glutamatergic synapses are the most prevalent functional elements of information
processing in the brain. Changes in pre-synaptic activity and in the function of various post …

[HTML][HTML] An ex vivo Model of Paired Cultured Hippocampal Neurons for Bi-directionally Studying Synaptic Transmission and Plasticity

R Stanika, GJ Obermair - Bio-protocol, 2023 - ncbi.nlm.nih.gov
Synapses provide the main route of signal transduction within neuronal networks. Many
factors regulate critical synaptic functions. These include presynaptic calcium channels …

Identification of Synaptic Integration Mode in CA3 Pyramidal Neuron Model

J Lorenzo, R Vuillaume, S Binczak… - 2019 9th International …, 2019 - ieeexplore.ieee.org
A morphologically realistic and anisotropic model of CA3 pyramidal neuron was developed
to determine the synaptic integration modes the neuron is able to perform. Linearity and …

Sensory-evoked activity in somatosensory cortex as a model to probe cortical plasticity in a mouse model of Rett syndrome

F Farhoomand - 2021 - dspace.library.uvic.ca
Rett syndrome (RTT), a severe neurodevelopmental disorder, affects females resulting from
loss-of-function mutations in the X-linked transcription factor methyl-CpG-binding protein 2 …

Specific CA3 neurons decode neural information of dentate granule cells evoked by paired-pulse stimulation in co-cultured networks

D Poli, TB DeMarse, BC Wheeler… - 2017 39th Annual …, 2017 - ieeexplore.ieee.org
CA3 and dentate gyrus (DG) neurons are cultured in two-chamber devices on multi-
electrode arrays (MEAs) and connected via micro-tunnels. In order to evoke time-locked …

Inter-regional Dynamics in Hippocampal Sub-Networks Co-cultured on Microelectrode Arrays and Connected via Micro-Tunnels

D Poli, TB DeMarse, GJ Brewer, BC Wheeler - EMBEC & NBC 2017: Joint …, 2018 - Springer
Different pairs of adjacent sub-regions of rat hippocampal neurons were co-cultured within
two-well devices on micro-electrode arrays (MEAs). Micro-tunnels allowed passage of …