Natural products as biofuels and bio-based chemicals: fatty acids and isoprenoids

HR Beller, TS Lee, L Katz - Natural product reports, 2015 - pubs.rsc.org
Covering: 2005 to 2015 Although natural products are best known for their use in medicine
and agriculture, a number of fatty acid-derived and isoprenoid natural products are being …

Synthetic biology for microbial production of lipid-based biofuels

L d'Espaux, D Mendez-Perez, R Li… - Current opinion in chemical …, 2015 - Elsevier
Highlights•Biological lipids are naturally energy-dense and several make good
biofuels.•Metabolic pathways to produce these biofuels have been engineered in microbial …

Biosynthesis, regulation, and engineering of microbially produced branched biofuels

W Bai, W Geng, S Wang, F Zhang - Biotechnology for biofuels, 2019 - Springer
The steadily increasing demand on transportation fuels calls for renewable fuel
replacements. This has attracted a growing amount of research to develop advanced …

Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases

JT Mindrebo, A Chen, WE Kim, RN Re, TD Davis… - ACS …, 2021 - ACS Publications
Ketosynthases (KSs) catalyze carbon–carbon bond-forming reactions in fatty acid synthases
(FASs) and polyketide synthases (PKSs). KSs utilize a two-step ping-pong kinetic …

Production of neo acids from biomass-derived monomers

E Andini, J Bragger, S Sadula, DG Vlachos - Green Chemistry, 2023 - pubs.rsc.org
Neo acids are highly branched carboxylic acids currently produced from fossil fuels. In this
work, we produce renewable neo acids from lignocellulosic biomass-derived furan and keto …

Steps towards 'drop-in'biofuels: focusing on metabolic pathways

W Jiang, P Gu, F Zhang - Current opinion in biotechnology, 2018 - Elsevier
Highlights•Four major metabolic pathways that lead to biofuel production are reviewed.•The
production of branched-chain fatty acid improved biofuel cold-flow properties.•Non …

Metabolic engineering for advanced biofuels production and recent advances toward commercialization

CW Meadows, A Kang, TS Lee - Biotechnology journal, 2018 - Wiley Online Library
Research on renewable biofuels produced by microorganisms has enjoyed considerable
advances in academic and industrial settings. As the renewable ethanol market approaches …

Strategies to Enhance the Biosynthesis of Monounsaturated Fatty Acids in Escherichia coli

P Matthay, T Schalck, N Verstraeten… - Biotechnology and …, 2023 - Springer
Fueled by a variety of industrial applications ranging from bioplastics to cosmetics and
pharmaceuticals, the global demand for unsaturated fatty acids is steadily rising. Most of …

A kinetic framework for modeling oleochemical biosynthesis in Escherichia coli

J Peoples, S Ruppe, K Mains… - Biotechnology and …, 2022 - Wiley Online Library
Microorganisms build fatty acids with biocatalytic assembly lines, or fatty acid synthases
(FASs), that can be repurposed to produce a broad set of fuels and chemicals. Despite their …

Microbial Production of Fatty Acid via Metabolic Engineering and Synthetic Biology

C Sathesh-Prabu, KS Shin, GH Kwak, SK Jung… - Biotechnology and …, 2019 - Springer
The microbial production of free fatty acids (FFAs) has gained great attention from the
scientific community due to its significant environmental and economic benefits. FFAs can …