Although motor deficits in humans with diabetic neuropathy have been extensively
researched, its effect on the motor system is thought to be lesser than that on the sensory …

Humans use their fingers to perform a variety of tasks, from simple grasping to manipulating
objects, to typing and playing musical instruments, a variety wider than any other species …

An account of the neurobiology of motor recovery in the arm and hand after stroke by two
experts in the field. Stroke is a leading cause of disability in adults and recovery is often …

The question of how intensive motor training restores motor function after brain damage or
stroke remains unresolved. Here we show that the ipsilesional ventral premotor cortex (PMv) …

The direct cortico-motoneuronal connection is believed to be essential for the control of
dexterous hand movements, such as precision grip in primates. It was reported, however …

Brain damage such as stroke is a devastating neurological condition that may severely
compromise patient quality of life. No effective medication-mediated intervention to …

Motivation facilitates recovery after neuronal damage, but its mechanism is elusive. It is
generally thought that the nucleus accumbens (NAc) regulates motivation-driven effort but is …

Evolutionally, development of the direct connection from the motor cortex to spinal
motoneurons [corticomotoneuronal (CM) pathway] parallels the ability of hand dexterity …

After spinal cord injury (SCI), the motor-related cortical areas can be a potential substrate for
functional recovery in addition to the spinal cord. However, a dynamic description of how …

Hand dexterity has uniquely developed in higher primates and is thought to rely on the direct
corticomotoneuronal (CM) pathway. Recent studies have shown that rodents and carnivores …