Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands

MA Krzyscik, K Karl, P Dudeja, P Krejci… - Cytokine & Growth Factor …, 2024 - Elsevier
The FGF system is the most complex of all receptor tyrosine kinase signaling networks with
18 FGF ligands and four FGFRs that deliver morphogenic signals to pattern most embryonic …

Investigations of membrane protein interactions in cells using fluorescence microscopy

M Abouelkheir, T Roy, MA Krzyscik, E Özdemir… - Current Opinion in …, 2024 - Elsevier
The interactions between proteins in membranes govern many cellular functions. Our ability
to probe for such interactions has greatly evolved in recent years due to the introduction of …

[PDF][PDF] In silico and vitro mapping of allosteric sites in GPCRs

T Ding - pure.qub.ac.uk
Allosteric modulators are considered to be promising candidates in G proteincoupled
receptor (GPCR) drug development by displaying subtype selectivity and more specific …