Serum albumin: a multifaced enzyme
G De Simone, A di Masi, P Ascenzi - International Journal of Molecular …, 2021 - mdpi.com
Human serum albumin (HSA) is the most abundant protein in plasma, contributing actively to
oncotic pressure maintenance and fluid distribution between body compartments. HSA acts …
oncotic pressure maintenance and fluid distribution between body compartments. HSA acts …
Structural and functional integrity of human serum albumin: Analytical approaches and clinical relevance in patients with liver cirrhosis
Human serum albumin (HSA) is the most abundant circulating plasma protein. Besides a
significant contribution to the osmotic pressure, it is also involved in the fine regulation of …
significant contribution to the osmotic pressure, it is also involved in the fine regulation of …
Reversible dimerization of human serum albumin
A Chubarov, A Spitsyna, O Krumkacheva, D Mitin… - Molecules, 2020 - mdpi.com
Pulsed Dipolar Spectroscopy (PDS) methods of Electron Paramagnetic Resonance (EPR)
were used to detect and characterize reversible non-covalent dimers of Human Serum …
were used to detect and characterize reversible non-covalent dimers of Human Serum …
Human serum albumin aggregation/fibrillation and its abilities to drugs binding
M Maciążek-Jurczyk, K Janas, J Pożycka, A Szkudlarek… - Molecules, 2020 - mdpi.com
Human serum albumin (HSA) is a protein that transports neutral and acid ligands in the
organism. Depending on the environment's pH conditions, HSA can take one of the five …
organism. Depending on the environment's pH conditions, HSA can take one of the five …
Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates
S Nirwal, V Bharathi, BK Patel - Biophysical Chemistry, 2021 - Elsevier
BSA can form amyloid-like aggregates in vitro at 65° C. Heterologous amyloid can
proposedly cross-seed other protein's aggregation, however, general mechanisms and …
proposedly cross-seed other protein's aggregation, however, general mechanisms and …
[HTML][HTML] Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins
Disulfide bonds play a key function in determining the structure of proteins, and are the most
strongly conserved compositional feature across proteomes. They are particularly common …
strongly conserved compositional feature across proteomes. They are particularly common …
Retention of anticancer activity of curcumin after conjugation with fluorescent gold quantum clusters: An in vitro and in vivo xenograft study
Gold nanoparticles (Au NPs) have been thoroughly investigated for anti-cancer therapy.
However, their undesired high gold content remains a problem when injected into the body …
However, their undesired high gold content remains a problem when injected into the body …
Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid …
Abstract TDP-43 is an RNA/DNA-binding protein which is also implicated in the
pathogenesis of amyotrophic lateral sclerosis (ALS) disease. TDP-43's cytoplasmic mis …
pathogenesis of amyotrophic lateral sclerosis (ALS) disease. TDP-43's cytoplasmic mis …
The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization
Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease
associated with accumulation of hyper-phosphorylated, and ubiquitinated TAR DNA-binding …
associated with accumulation of hyper-phosphorylated, and ubiquitinated TAR DNA-binding …
Wild-type hen egg white lysozyme aggregation in vitro can form self-seeding amyloid conformational variants
V Sivalingam, NL Prasanna, N Sharma, A Prasad… - Biophysical …, 2016 - Elsevier
Misfolded β-sheet-rich protein aggregates termed amyloid, deposit in vivo leading to
debilitating diseases such as Alzheimer's, prion and renal amyloidosis diseases etc …
debilitating diseases such as Alzheimer's, prion and renal amyloidosis diseases etc …