Humans live in a 24-hour environment, in which light and darkness follow a diurnal pattern.
Our circadian pacemaker, the suprachiasmatic nuclei (SCN) in the hypothalamus, is …

Given the large proportion of time spent by the average person indoors, it is imperative to
have an understanding of the impacts of long-term and immersive exposure to a variety of …

Light around twilight provides the primary entrainment signal for circadian rhythms. Here we
review the mechanisms and responses of the mouse and human circadian systems to light …

Introduction Light elicits a range of non‐visual responses in humans. Driven predominantly
by intrinsically photosensitive retinal ganglion cells (ipRGCs), but also by rods and/or cones …

The circadian system in animals and humans, being near but not exactly 24 hours in cycle
length, must be reset on a daily basis to remain in synchrony with external environmental …

Objective: This the first of two articles reviewing the scientific literature on the evaluation and
treatment of circadian rhythm sleep disorders (CRSDs), employing the methodology of …

The periodic light-dark cycle is the dominant environmental synchronizer used by humans to
entrain to the geophysical 24-h day. Entrainment is a fundamental property of circadian …

Key points• Light is the strongest time cue for entrainment and phase resetting of the
circadian clock.• In humans, exposure to long‐duration light (6.5 h) in the late evening/early …

The number of travellers undertaking long-distance flights has continued to increase. Such
flights are associated with travel fatigue and jet lag, the symptoms of which are considered …

During the past 50 years, converging evidence reveals that the fundamental properties of
the human circadian system are shared in common with those of other organisms …