Fisetin, potential flavonoid with multifarious targets for treating neurological disorders: An updated review

AR Ravula, SB Teegala, S Kalakotla… - European journal of …, 2021 - Elsevier
Neurodegenerative disorders pose a significant health burden and imprint a debilitative
impact on the quality of life. Importantly, aging is intricately intertwined with the progression …

Cellular and molecular mechanisms mediating methylmercury neurotoxicity and neuroinflammation

JP Novo, B Martins, RS Raposo, FC Pereira… - International journal of …, 2021 - mdpi.com
Methylmercury (MeHg) toxicity is a major environmental concern. In the aquatic reservoir,
MeHg bioaccumulates along the food chain until it is consumed by riverine populations …

Effect of methylmercury on fetal neurobehavioral development: an overview of the possible mechanisms of toxicity and the neuroprotective effect of phytochemicals

G Bjørklund, H Antonyak, A Polishchuk… - Archives of …, 2022 - Springer
Methylmercury (MeHg) is a global environmental pollutant with neurotoxic effects. Exposure
to MeHg via consumption of seafood and fish can severely impact fetal neurobehavioral …

The Neuroprotective Role of Fisetin in Different Neurological Diseases: A Systematic Review

Y Jiang, X Tang, P Deng, C Jiang, Y He, D Hao… - Molecular …, 2023 - Springer
Neurological diseases place a substantial burden on public health and have a serious
impact on the quality of life of patients. Despite the multifaceted pathological process …

[HTML][HTML] Cognitive outcomes caused by low-level lead, cadmium, and mercury mixture exposure at distinct phases of brain development

L Ouyang, Q Li, S Rao, R Su, Y Zhu, G Du, J Xie… - Food and Chemical …, 2023 - Elsevier
Contaminated water and food are the main sources of lead, cadmium, and mercury in the
human body. Long-term and low-level ingestion of these toxic heavy metals may affect brain …

[HTML][HTML] Combining in vitro assays and mathematical modelling to study developmental neurotoxicity induced by chemical mixtures

F Pistollato, D Carpi, E Mendoza-de Gyves… - Reproductive …, 2021 - Elsevier
Prenatal and postnatal co-exposure to multiple chemicals at the same time may have
deleterious effects on the developing nervous system. We previously showed that chemicals …

Mechanisms of oxidative stress in methylmercury-induced neurodevelopmental toxicity

X Li, J Pan, Y Wei, L Ni, B Xu, Y Deng, T Yang, W Liu - Neurotoxicology, 2021 - Elsevier
Methylmercury (MeHg) is a long-lasting organic environmental pollutant that poses a great
threat to human health. Ingestion of seafood containing MeHg is the most important way by …

The roles of histone modifications in metal-induced neurological disorders

Y Wu, R Wang, R Liu, Y Ba, H Huang - Biological Trace Element Research, 2023 - Springer
Increasing research is illuminating the intricate roles of metal ions in neural development as
well as neurological disorders, which may stem from misregulation or dysfunction of …

Prenatal amoxicillin exposure induces developmental toxicity in fetal mice and its characteristics

Y Dai, Y Peng, W Hu, Y Liu, H Wang - Journal of Environmental Sciences, 2024 - Elsevier
Amoxicillin, a widely used antibiotic in human and veterinary pharmaceuticals, is now
considered as an “emerging contaminant” because it exists widespreadly in the environment …

An Overview of Recent Advances in the Neuroprotective Potentials of Fisetin against Diverse Insults in Neurological Diseases and the Underlying Signaling Pathways

X Tang, P Deng, Y Jiang, L Zhang, Y He, H Yang - Biomedicines, 2023 - mdpi.com
The nervous system plays a leading role in the regulation of physiological functions and
activities in the body. However, a variety of diseases related to the nervous system have a …