[HTML][HTML] Exosome composition and seminal plasma proteome: A promising source of biomarkers of male infertility

L Candenas, R Chianese - International journal of molecular sciences, 2020 - mdpi.com
Infertility has become a global health issue, with approximately 50% of infertility cases
generated by disorders in male reproduction. Spermatozoa are conveyed towards female …

[HTML][HTML] The enigmatic seminal plasma: a proteomics insight from ejaculation to fertilization

L Samanta, R Parida, TR Dias, A Agarwal - Reproductive Biology and …, 2018 - Springer
Background The 'omics' approach for a noninvasive diagnosis of male reproductive system
disorders has gained momentum during the last decade, particularly from a screening and …

[HTML][HTML] MiOXSYS: a novel method of measuring oxidation reduction potential in semen and seminal plasma

A Agarwal, R Sharma, S Roychoudhury, S Du Plessis… - Fertility and sterility, 2016 - Elsevier
Objective To measure oxidative reduction potential (ORP) in semen and seminal plasma
and to establish their reference levels. Design ORP levels were measured in semen and …

Diagnostic application of oxidation-reduction potential assay for measurement of oxidative stress: clinical utility in male factor infertility

A Agarwal, S Roychoudhury, R Sharma, S Gupta… - Reproductive …, 2017 - Elsevier
The objectives of this study were to:(i) describe a protocol measuring the oxidation-reduction
potential (ORP) by MiOXSYS System as an alternative method of seminal oxidative stress …

The influence of seminal plasma on offspring development and health

HL Morgan, AJ Watkins - Seminars in cell & developmental biology, 2020 - Elsevier
The concept that a father's wellbeing at the time of conception influences the development
and long-term health of his offspring is now well established. However, the mechanisms …

Heat stress response of somatic cells in the testis

RA Aldahhan, PG Stanton - Molecular and Cellular Endocrinology, 2021 - Elsevier
The testis is a temperature-sensitive organ that needs to be maintained 2–7° C below core
body temperature to ensure the production of normal sperm. Failure to maintain testicular …

HBFP: a new repository for human body fluid proteome

D Shao, L Huang, Y Wang, X Cui, Y Li, Y Wang… - Database, 2021 - academic.oup.com
Body fluid proteome has been intensively studied as a primary source for disease biomarker
discovery. Using advanced proteomics technologies, early research success has resulted in …

[HTML][HTML] Seminal plasma proteomic biomarkers of oxidative stress

R Cannarella, A Crafa, F Barbagallo… - International Journal of …, 2020 - mdpi.com
The prevalence of idiopathic male infertility is high, up to 75% of patients with abnormal
sperm parameters. Hence, the research of its causes is mandatory. Oxidative stress (OS) …

[HTML][HTML] Sperm proteome analysis and identification of fertility-associated biomarkers in unexplained male infertility

MK Panner Selvam, A Agarwal, PN Pushparaj… - Genes, 2019 - mdpi.com
Up to 30% of men with normal semen parameters suffer from infertility and the reason for this
is unknown. Altered expression of sperm proteins may be a major cause of infertility in these …

[HTML][HTML] Decrease in Sperm Parameters in the 21st Century: Obesity, Lifestyle, or Environmental Factors? An Updated Narrative Review

R Sciorio, L Tramontano, M Adel, S Fleming - Journal of Personalized …, 2024 - mdpi.com
Semen quality represents a compelling factor for fertility, and delineating the normal values
has proven difficult. In the last four decades, several authors have reported a noticeable …