[HTML][HTML] Glucocorticoid receptor signaling in diabetes
I Kokkinopoulou, A Diakoumi, P Moutsatsou - International journal of …, 2021 - mdpi.com
Stress and depression increase the risk of Type 2 Diabetes (T2D) development. Evidence
demonstrates that the Glucocorticoid (GC) negative feedback is impaired (GC resistance) in …
demonstrates that the Glucocorticoid (GC) negative feedback is impaired (GC resistance) in …
Chronic Stress as a Risk Factor for Type 2 Diabetes: Endocrine, Metabolic, and Immune Implications
G Lisco, VA Giagulli, G De Pergola… - … Metabolic & Immune …, 2024 - ingentaconnect.com
Background: Chronic stress is a condition of pressure on the brain and whole body, which in
the long term may lead to a frank disease status, even including type 2 diabetes (T2D) …
the long term may lead to a frank disease status, even including type 2 diabetes (T2D) …
[HTML][HTML] RNA sequencing-based identification of the regulatory mechanism of microRNAs, transcription factors, and corresponding target genes involved in vascular …
K Zhao, L Zeng, Z Cai, M Liu, T Sun, Z Li… - Frontiers in …, 2022 - frontiersin.org
Vascular dementia (VaD) is the second most common form of dementia with uncertain
mechanisms and no effective treatments. microRNAs (miRNAs) and transcription factors …
mechanisms and no effective treatments. microRNAs (miRNAs) and transcription factors …
Update on the role of glucocorticoid signaling in osteoblasts and bone marrow adipocytes during aging
H Bensreti, DW Alhamad, AM Gonzalez… - Current osteoporosis …, 2023 - Springer
Abstract Purpose of Review Bone marrow adipose tissue (BMAT) in the skeleton likely plays
a variety of physiological and pathophysiological roles that are not yet fully understood. In …
a variety of physiological and pathophysiological roles that are not yet fully understood. In …
[HTML][HTML] Icariin inhibits epithelial mesenchymal transition of renal tubular epithelial cells via regulating the miR-122-5p/FOXP2 axis in diabetic nephropathy rats
L Zang, F Gao, A Huang, Y Zhang, Y Luo… - Journal of …, 2022 - Elsevier
Epithelial mesenchymal transition (EMT) of renal tubular epithelial cells (RTECs) dominates
the pathology of diabetic nephropathy (DN). microRNAs (miRNAs) can influence the fate of …
the pathology of diabetic nephropathy (DN). microRNAs (miRNAs) can influence the fate of …
[HTML][HTML] FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice
D Zhu, J Lu, R Xu, J Yang, X Meng… - Acta Pharmacologica …, 2022 - nature.com
Diabetic cognitive impairment (DCI) is a common diabetic complication characterized by
learning and memory deficits. In diabetic patients, hyperactivated hypothalamic-pituitary …
learning and memory deficits. In diabetic patients, hyperactivated hypothalamic-pituitary …
[HTML][HTML] Unlocking therapeutic potential: exploring cross-talk among emerging nuclear receptors to combat metabolic dysfunction in steatotic liver disease
MB Antwi, A Jennings, S Lefere, D Clarisse… - npj Metabolic Health …, 2024 - nature.com
Nuclear receptors (NRs) regulate cellular processes and serve as key targets in treating
metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis …
metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis …
Small Molecular Compound FX5 as a Non-Steroidal GR Antagonist Ameliorates Diabetic Cognitive Impairment in Mice
J Lu, R Xu, T Zhao, Y Chen, Y Lu, X Shen - papers.ssrn.com
Background: Diabetic cognitive impairment (DCI) is a commonly diabetic complication with
structural and biophysiological dysfunctions in the brain. The injured hypothalamic-pituitary …
structural and biophysiological dysfunctions in the brain. The injured hypothalamic-pituitary …