Haematopoietic stem cells (HSCs) emerge during embryogenesis and give rise to the adult
haematopoietic system. Understanding how early haematopoietic development occurs is of …

Human pluripotent stem cells (hPSCs) provide an unparalleled opportunity to establish in
vitro differentiation models that will transform our approach to the study of human …

Hematopoietic stem cells (HSCs) are the rare cells responsible for the lifelong curative
effects of hematopoietic cell (HC) transplantation. The demand for clinical-grade HSCs has …

Stem cells of the gastrointestinal tract, pancreas, liver and other columnar epithelia
collectively resist cloning in their elemental states. Here we demonstrate the cloning and …

In vitro generation of hematopoietic stem cells (HSCs) from induced pluripotent stem cells
(iPSCs) has the potential to provide novel therapeutic approaches for replacing bone …

Cell engineering has brought us tantalizingly close to the goal of deriving patient-specific
hematopoietic stem cells (HSCs). While directed differentiation and transcription factor …

Generating human hematopoietic stem cells (HSCs) from autologous tissues, when coupled
with genome editing technologies, is a promising approach for cellular transplantation …

Hematopoietic stem cell transplantation (HSCT) is the first field where human stem cell
therapy was successful. Flooding interest on human stem cell therapy to cure previously …

The generation of hematopoietic stem cells (HSCs) from induced pluripotent stem cells
(iPSCs) is an active and promising area of research; however, generating engraftable HSCs …

Significant advances in cellular reprogramming technologies and hematopoietic
differentiation from human pluripotent stem cells (hPSCs) have already enabled the routine …