Molecular imaging of extracellular matrix proteins with targeted probes using magnetic resonance imaging

M Salarian, OY Ibhagui, JJ Yang - … Reviews: Nanomedicine and …, 2020 - Wiley Online Library
The extracellular matrix (ECM) consists of proteins and carbohydrates that supports different
biological structures and processes such as tissue development, elasticity, and preservation …

Strategies for target-specific contrast agents for magnetic resonance imaging

SM Vithanarachchi, MJ Allen - Current Molecular Imaging …, 2012 - ingentaconnect.com
This review describes recent research efforts focused on increasing the specificity of contrast
agents for proton magnetic resonance imaging (MRI). Contrast agents play an …

Eu II-containing cryptates as contrast agents for ultra-high field strength magnetic resonance imaging

J Garcia, J Neelavalli, EM Haacke… - Chemical …, 2011 - pubs.rsc.org
The relaxivity (contrast-enhancing ability) of EuII-containing cryptates was found to be better
than a clinically approved GdIII-based agent at 7 T. These cryptates are among a few …

Physical Properties of Eu2+‐Containing Cryptates as Contrast Agents for Ultrahigh‐Field Magnetic Resonance Imaging

J Garcia, ANW Kuda‐Wedagedara… - European journal of …, 2012 - Wiley Online Library
The kinetic stabilities and relaxivities of a series of Eu2+‐containing cryptates have been
investigated. Transmetallation studies, which monitored the change in the longitudinal …

Study of the lanthanide-catalyzed, aqueous, asymmetric Mukaiyama aldol reaction

Y Mei, DJ Averill, MJ Allen - The Journal of Organic Chemistry, 2012 - ACS Publications
The development of efficient methods for the asymmetric Mukaiyama aldol reaction in
aqueous solution has received great attention. We have developed a new series of chiral …

Aqueous lanthanide chemistry in asymmetric catalysis and magnetic resonance imaging

MJ Allen - Synlett, 2016 - thieme-connect.com
This account describes lanthanide coordination chemistry with a focus on the similarities
between lanthanide complexes used in catalysis and those used as contrast agents in …

Paramagnetic relaxation enhancement for protein-observed 19 F NMR as an enabling approach for efficient fragment screening

LML Hawk, CT Gee, AK Urick, H Hu, WCK Pomerantz - RSC advances, 2016 - pubs.rsc.org
Protein-observed 19F (PrOF) NMR is an emerging tool for ligand discovery. To optimize the
efficiency of PrOF NMR experiments, paramagnetic relaxation enhancement through the …

A multimodal, β-amyloid-targeted contrast agent

SM Vithanarachchi, MJ Allen - Chemical Communications, 2013 - pubs.rsc.org
A multimodal, β-amyloid-targeted contrast agent - Chemical Communications (RSC Publishing)
DOI:10.1039/C2CC36583A Royal Society of Chemistry View PDF VersionPrevious ArticleNext …

General synthetic and physical methods

QN Do, JS Ratnakar, Z Kovács, G Tircsó… - 2017 - books.rsc.org
A large number of open-chain, macrocyclic, and hybrid complexes have been reported as
diagnostic, therapeutic, and theranostic agents. Lanthanide and transition-metal ions, which …

A (Fluoroalkyl) guanidine modulates the relaxivity of a phosphonate-containing T1-shortening contrast agent

X Wu, AC Dawsey, BN Siriwardena-Mahanama… - Journal of fluorine …, 2014 - Elsevier
Responsive magnetic resonance imaging (MRI) contrast agents, those that change their
relaxivity according to environmental stimuli, have promise as next generation imaging …