Genome editing is the modification of genomic DNA at a specific target site in a wide variety
of cell types and organisms, including insertion, deletion and replacement of DNA, resulting …

The physiological process of biomineralization is complex and deviation from it leads to a
variety of diseases. Progress in the past 10 years has enhanced understanding of the …

BMP signaling plays an important role in dentin development. BMPs and antagonists
regulate odontoblast differentiation and downstream gene expression via canonical Smad …

Abstract Glucocorticoid (GC; dexamethasone, DEX)‐induced osteonecrosis of the femoral
head (GIOFH) is a challenging orthopedic disease, and its underlying mechanism remains …

Since phosphorus is a component of hydroxyapatite, its prolonged deprivation affects bone
mineralization. Fibroblast growth factor 23 (FGF23) is essential for maintaining phosphate …

Objective Using a mouse osteoporotic model, this study aimed to determine the influence of
hydrophilic titanium surfaces on gene expression and bone formation during the …

Bone-forming osteoblasts have been a cornerstone of bone biology for more than a century.
Most research toward bone biology and bone diseases center on osteoblasts. Overlooked …

The maternal skeleton experiences significant bone loss during lactation, followed by rapid
restoration post weaning. Parathyroid-related protein (PTHrP)-induced acidification of the …

The vertebrate musculoskeletal system is known to be formed by mesenchymal stem cells
condensing into tissue elements, which then differentiate into cartilage, bone …

Vital pulp preservation, which is a clinical challenge of aseptic or iatrogenic accidental
exposure of the pulp, in cases direct pulp capping is the main technology. Human dental …