Congenital adrenal hyperplasia due to 11 beta-hydroxylase deficiency is a rare autosomal
recessive genetic disorder. It is caused by reduced or absent activity of 11β-hydroxylase …

Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young,
appearing in the fossil record during the Cambrian explosion about 542 to 515 million years …

The indigenous people of Greenland, the Inuit, have lived for a long time in the extreme
conditions of the Arctic, including low annual temperatures, and with a specialized diet rich …

Androgen is essential for male development and cortisol is involved in reproduction in
fishes. However, the in vivo roles of cortisol and specific androgens such as 11 …

Many responses to adrenal and sex steroids are mediated by receptors that belong to the
nuclear receptor family of transcription factors. We investigated the co-evolution of these …

Aldosterone and cortisol serve important roles in the pathogenesis of cardiovascular
diseases and metabolic disorders. Epigenetics is a mechanism to control enzyme …

Background Human fetal adrenal glands are highly active and, with the placenta, regulate
circulating progesterone, estrogen and corticosteroids in the fetus. At birth the adrenals are …

Aldosterone is the major mineralocorticoid in the human body controlling blood pressure
and salt homeostasis. Overproduction of aldosterone leads to primary aldosteronism, which …

Steroidal resource occupies a vital proportion in the pharmaceutical industry attributing to
their important therapeutic effects on fertility, anti-inflammatory and antiviral activities …

The radiation-induced bystander effect (RIBE) is the initiation of biological end points in cells
(bystander cells) that are not directly traversed by an incident-radiation track, but are in close …