Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity
The current obesity pandemic results from a physiological imbalance in which energy intake
chronically exceeds energy expenditure (EE), and prevention and treatment strategies …
chronically exceeds energy expenditure (EE), and prevention and treatment strategies …
A tangled threesome: circadian rhythm, body temperature variations, and the immune system
Simple Summary In mammals, including humans, the body temperature displays a circadian
rhythm and is maintained within a narrow range to facilitate the optimal functioning of …
rhythm and is maintained within a narrow range to facilitate the optimal functioning of …
Neonatal infrared thermography images in the hypothermic ruminant model: Anatomical-morphological-physiological aspects and mechanisms for thermoregulation
Hypothermia is one factor associated with mortality in newborn ruminants due to the drastic
temperature change upon exposure to the extrauterine environment in the first hours after …
temperature change upon exposure to the extrauterine environment in the first hours after …
Cold exposure protects against medial arterial calcification development via autophagy
FXZ Li, JJ Liu, F Xu, SK Shan, MH Zheng… - Journal of …, 2023 - Springer
Medial arterial calcification (MAC), a systemic vascular disease different from
atherosclerosis, is associated with an increased incidence of cardiovascular events. Several …
atherosclerosis, is associated with an increased incidence of cardiovascular events. Several …
Primate preoptic neurons drive hypothermia and cold defense
Maintaining body temperature within a narrow range is vital for warm-blooded animals. In
rodents, the preoptic area (POA) of the hypothalamus detects and regulates core body …
rodents, the preoptic area (POA) of the hypothalamus detects and regulates core body …
5-HT receptors and temperature homeostasis
IP Voronova - Biomolecules, 2021 - mdpi.com
The present review summarizes the data concerning the influence of serotonin (5-HT)
receptors on body temperature in warm-blooded animals and on processes associated with …
receptors on body temperature in warm-blooded animals and on processes associated with …
Is upregulation of sarcolipin beneficial or detrimental to muscle function?
Sarcolipin (SLN) is a regulator of sarco/endo plasmic reticulum Ca2+-ATPase (SERCA)
pump and has been shown to be involved in muscle nonshivering thermogenesis (NST) and …
pump and has been shown to be involved in muscle nonshivering thermogenesis (NST) and …
Seven days of cold acclimation substantially reduces shivering intensity and increases nonshivering thermogenesis in adult humans
K Gordon, DP Blondin, BJ Friesen… - Journal of Applied …, 2019 - journals.physiology.org
Daily compensable cold exposure in humans reduces shivering by~ 20% without changing
total heat production, partly by increasing brown adipose tissue thermogenic capacity and …
total heat production, partly by increasing brown adipose tissue thermogenic capacity and …
The long way of oxytocin from the uterus to the heart in 70 years from its discovery
C Camerino - International Journal of Molecular Sciences, 2023 - mdpi.com
The research program on oxytocin started in 1895, when Oliver and Schafer reported that a
substance extracted from the pituitary gland elevates blood pressure when injected …
substance extracted from the pituitary gland elevates blood pressure when injected …
Examining the benefits of cold exposure as a therapeutic strategy for obesity and type 2 diabetes
YM Ivanova, DP Blondin - Journal of Applied Physiology, 2021 - journals.physiology.org
The pathogenesis of metabolic diseases such as obesity and type 2 diabetes are
characterized by a progressive dysregulation in energy partitioning, often leading to end …
characterized by a progressive dysregulation in energy partitioning, often leading to end …